Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain

Carlie L. Cullen, Renee E. Pepper, Mackenzie T. Clutterbuck, Kimberley A. Pitman, Viola Oorschot, Loic Auderset, Alexander D. Tang, Georg Ramm, Ben Emery, Jennifer Rodger, Renaud B. Jolivet, Kaylene M. Young

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Cullen et al. show that mature brain cells, called oligodendrocytes, undergo ultrastructural changes during learning. They lengthen the nodes of Ranvier and compress the periaxonal space to speed up action potential conduction. They also report that faster information transfer speeds correlate with greater skill acquisition during learning.

Original languageEnglish
Article number108641
JournalCell Reports
Volume34
Issue number3
DOIs
Publication statusPublished - 19 Jan 2021

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