Pediatric asthma: An unmet need for more effective, focused treatments

Nikolaos G. Papadopoulos; Adnan Custovic; Michael D. Cabana; Sharon D. Dell; Antoine Deschildre; Gunilla Hedlin; Elham Hossny; Peter Le Souef; Paolo M. Matricardi; Antonio Nieto; Wanda Phipatanakul; Paulo M. Pitrez; Petr Pohunek; Marcela Gavornikova; Xavier Jaumont; David B. Price

doi:10.1111/pai.12990

Pediatric asthma: An unmet need for more effective, focused treatments

Nikolaos G. Papadopoulos, Adnan Custovic, Michael D. Cabana, Sharon D. Dell, Antoine Deschildre, Gunilla Hedlin, Elham Hossny, Peter Le Souef, Paolo M. Matricardi, Antonio Nieto, Wanda Phipatanakul, Paulo M. Pitrez, Petr Pohunek, Marcela Gavornikova, Xavier Jaumont, David B. Price

Paediatrics

Research output: Contribution to journal › Review article › peer-review

39 Citations (Scopus)

Abstract

Background Despite remarkable advances in our understanding of asthma, there are still several unmet needs associated with the management of pediatric asthma. Methods A two-day, face-to-face meeting was held in London, United Kingdom, on October 28 and 29, 2017, involving a group of international expert clinicians and scientists in asthma management to discuss the challenges and unmet needs that remain to be addressed in pediatric asthma. Results These unmet needs include a lack of clinical efficacy and safety evidence, and limited availability of non-steroid-based alternative therapies in patients

Original language	English
Pages (from-to)	7-16
Number of pages	10
Journal	Pediatric Allergy and Immunology
Volume	30
Issue number	1
DOIs	https://doi.org/10.1111/pai.12990
Publication status	Published - Feb 2019

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10.1111/pai.12990Licence: CC BY-NC

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Papadopoulos, N. G., Custovic, A., Cabana, M. D., Dell, S. D., Deschildre, A., Hedlin, G., Hossny, E., Le Souef, P., Matricardi, P. M., Nieto, A., Phipatanakul, W., Pitrez, P. M., Pohunek, P., Gavornikova, M., Jaumont, X., & Price, D. B. (2019). Pediatric asthma: An unmet need for more effective, focused treatments. Pediatric Allergy and Immunology, 30(1), 7-16. https://doi.org/10.1111/pai.12990

@article{e45927281f70468fb09cb9832eae7b7e,

title = "Pediatric asthma: An unmet need for more effective, focused treatments",

abstract = "Background Despite remarkable advances in our understanding of asthma, there are still several unmet needs associated with the management of pediatric asthma. Methods A two-day, face-to-face meeting was held in London, United Kingdom, on October 28 and 29, 2017, involving a group of international expert clinicians and scientists in asthma management to discuss the challenges and unmet needs that remain to be addressed in pediatric asthma. Results These unmet needs include a lack of clinical efficacy and safety evidence, and limited availability of non-steroid-based alternative therapies in patients",

keywords = "asthma management, omalizumab, pediatric asthma, unmet need, BONE-MINERAL DENSITY, INHALED CORTICOSTEROIDS, ALLERGIC-ASTHMA, PREDICTIVE-VALUE, IGE RESPONSES, DOUBLE-BLIND, CHILDREN, OMALIZUMAB, MANAGEMENT, CHILDHOOD",

author = "Papadopoulos, {Nikolaos G.} and Adnan Custovic and Cabana, {Michael D.} and Dell, {Sharon D.} and Antoine Deschildre and Gunilla Hedlin and Elham Hossny and {Le Souef}, Peter and Matricardi, {Paolo M.} and Antonio Nieto and Wanda Phipatanakul and Pitrez, {Paulo M.} and Petr Pohunek and Marcela Gavornikova and Xavier Jaumont and Price, {David B.}",

year = "2019",

month = feb,

doi = "10.1111/pai.12990",

language = "English",

volume = "30",

pages = "7--16",

journal = "Pediatric Allergy & Immunology",

issn = "0905-6157",

publisher = "Blackwell",

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Papadopoulos, NG, Custovic, A, Cabana, MD, Dell, SD, Deschildre, A, Hedlin, G, Hossny, E, Le Souef, P, Matricardi, PM, Nieto, A, Phipatanakul, W, Pitrez, PM, Pohunek, P, Gavornikova, M, Jaumont, X & Price, DB 2019, 'Pediatric asthma: An unmet need for more effective, focused treatments', Pediatric Allergy and Immunology, vol. 30, no. 1, pp. 7-16. https://doi.org/10.1111/pai.12990

TY - JOUR

T1 - Pediatric asthma

T2 - An unmet need for more effective, focused treatments

AU - Papadopoulos, Nikolaos G.

AU - Custovic, Adnan

AU - Cabana, Michael D.

AU - Dell, Sharon D.

AU - Deschildre, Antoine

AU - Hedlin, Gunilla

AU - Hossny, Elham

AU - Le Souef, Peter

AU - Matricardi, Paolo M.

AU - Nieto, Antonio

AU - Phipatanakul, Wanda

AU - Pitrez, Paulo M.

AU - Pohunek, Petr

AU - Gavornikova, Marcela

AU - Jaumont, Xavier

AU - Price, David B.

PY - 2019/2

Y1 - 2019/2

N2 - Background Despite remarkable advances in our understanding of asthma, there are still several unmet needs associated with the management of pediatric asthma. Methods A two-day, face-to-face meeting was held in London, United Kingdom, on October 28 and 29, 2017, involving a group of international expert clinicians and scientists in asthma management to discuss the challenges and unmet needs that remain to be addressed in pediatric asthma. Results These unmet needs include a lack of clinical efficacy and safety evidence, and limited availability of non-steroid-based alternative therapies in patients

AB - Background Despite remarkable advances in our understanding of asthma, there are still several unmet needs associated with the management of pediatric asthma. Methods A two-day, face-to-face meeting was held in London, United Kingdom, on October 28 and 29, 2017, involving a group of international expert clinicians and scientists in asthma management to discuss the challenges and unmet needs that remain to be addressed in pediatric asthma. Results These unmet needs include a lack of clinical efficacy and safety evidence, and limited availability of non-steroid-based alternative therapies in patients

KW - asthma management

KW - omalizumab

KW - pediatric asthma

KW - unmet need

KW - BONE-MINERAL DENSITY

KW - INHALED CORTICOSTEROIDS

KW - ALLERGIC-ASTHMA

KW - PREDICTIVE-VALUE

KW - IGE RESPONSES

KW - DOUBLE-BLIND

KW - CHILDREN

KW - OMALIZUMAB

KW - MANAGEMENT

KW - CHILDHOOD

U2 - 10.1111/pai.12990

DO - 10.1111/pai.12990

M3 - Review article

C2 - 30312503

VL - 30

SP - 7

EP - 16

JO - Pediatric Allergy & Immunology

JF - Pediatric Allergy & Immunology

SN - 0905-6157

IS - 1

ER -

Pediatric asthma: An unmet need for more effective, focused treatments

Abstract

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