Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients' management

J. Golledge, Paul Norman

    Research output: Contribution to journalArticlepeer-review

    53 Citations (Scopus)


    Purpose of reviewAbdominal aortic aneurysm (AAA) is being diagnosed more frequently in older patientsdue to the increased use of abdominal imaging and the rising average age of westernpopulations. Currently the management of this condition has two important deficiencies:inadequate methods to identify AAAs at risk of progression and rupture and thecurrent lack of effective nonsurgical therapies. In this review recent developments inidentifying new diagnostic, prognostic and therapeutic strategies for AAA are discussed.Recent findingsThere are growing number of animal and human association studies which haveidentified markers and strategies of potential value in improving identification,monitoring and treatment of AAA.SummarySelective large prospective imaging, biomarker and intervention studies are nowrequired to clearly demonstrate the value of new management pathways for AAA.
    Original languageEnglish
    Pages (from-to)532-538
    JournalCurrent Opinion in Cardiology
    Issue number6
    Publication statusPublished - 2009


    Dive into the research topics of 'Pathophysiology of abdominal aortic aneurysm relevant to improvements in patients' management'. Together they form a unique fingerprint.

    Cite this