Pasteurization of donor human milk for the use in the neonatal intensive care unit

Lukas Christen

Research output: ThesisDoctoral Thesis

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Abstract

[Truncated abstract] Donor human milk is the best alternative when mothers' own milk is not available for preterm infants. However, to prevent the transmission of pathogens from a donor to an infant the donor human milk is pasteurized. The pasteurization process is defined by national local milk banking guidelines but is commonly the Holder pasteurization. Holder pasteurization (62.5ºC for 30 minutes) is capable of destroying common vegetative bascteria and viruses found in human milk. However, bioactive components such as proteins and vitamins are largely inactivated. This thesis hypothesizes the alternative pasteurization methods applied to human milk can minimize the loss of these bioactive components while keeping the same high safety standard for the preterm infant. The aim of this thesis was to investigate the effect of two alternative pasteurization methods, ultrasoniation and ultravilet irradiation, on human milk.
Original languageEnglish
QualificationDoctor of Philosophy
Publication statusUnpublished - 2014

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