Paracrine Wnt mediators in decidual-placental communication

Sarmah Bin Nayeem

    Research output: ThesisMaster's Thesis

    103 Downloads (Pure)

    Abstract

    [Truncated] The integration of a complex network of signalling molecules promotes implantation of blastocyst and the development of placenta. These processes are crucial for a successful pregnancy and optimal fetal growth and development. The signalling network involves both cell-to-cell and cell-to-extracellular matrix communication. The family of secreted glycoprotein ligands, Wnts, plays a major role in regulating a wide range of biological processes, including embryonic development, cell fate, proliferation, migration, stem cell maintenance, tumour suppression, oncogenesis and tissue homeostasis.
    Original languageEnglish
    QualificationMasters
    Publication statusUnpublished - Sep 2014

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