Paracetamol allergy in clinical practice

Research output: Contribution to journalReview article

Abstract

Background: Paracetamol is a widely used analgesic to which hypersensitivity reactions are rare. Reactions to paracetamol May be due to the pharmacological effects of cyclooxygenase-1 inhibition or, more rarely, due to a selective allergy against paracetamol.

Objective: This article aims to review the current literature in the context of two cases seen in the authors' allergy practice.

Discussion: Paracetamol allergy is uncommon and, as a result, May be overlooked as a cause for immediate hypersensitivity, which can lead to a significant delay in diagnosis. Currently, specialist referral for a supervised oral challenge is required for formal diagnosis.
Original languageEnglish
Pages (from-to)216-219
Number of pages4
JournalAustralian journal of general practice
Volume48
Issue number4
Publication statusPublished - 10 Apr 2019

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