Paracetamol allergy in clinical practice

Research output: Contribution to journalReview article

Abstract

Background: Paracetamol is a widely used analgesic to which hypersensitivity reactions are rare. Reactions to paracetamol May be due to the pharmacological effects of cyclooxygenase-1 inhibition or, more rarely, due to a selective allergy against paracetamol.

Objective: This article aims to review the current literature in the context of two cases seen in the authors' allergy practice.

Discussion: Paracetamol allergy is uncommon and, as a result, May be overlooked as a cause for immediate hypersensitivity, which can lead to a significant delay in diagnosis. Currently, specialist referral for a supervised oral challenge is required for formal diagnosis.
Original languageEnglish
Pages (from-to)216-219
Number of pages4
JournalAustralian journal of general practice
Volume48
Issue number4
Publication statusPublished - 10 Apr 2019

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Acetaminophen
Hypersensitivity
Immediate Hypersensitivity
Cyclooxygenase 1
Analgesics
Referral and Consultation
Pharmacology

Cite this

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title = "Paracetamol allergy in clinical practice",
abstract = "Background: Paracetamol is a widely used analgesic to which hypersensitivity reactions are rare. Reactions to paracetamol May be due to the pharmacological effects of cyclooxygenase-1 inhibition or, more rarely, due to a selective allergy against paracetamol.Objective: This article aims to review the current literature in the context of two cases seen in the authors' allergy practice.Discussion: Paracetamol allergy is uncommon and, as a result, May be overlooked as a cause for immediate hypersensitivity, which can lead to a significant delay in diagnosis. Currently, specialist referral for a supervised oral challenge is required for formal diagnosis.",
author = "Grace Thompson and Christine Bundell and Michaela Lucas",
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pages = "216--219",
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Paracetamol allergy in clinical practice. / Thompson, Grace; Bundell, Christine; Lucas, Michaela.

In: Australian journal of general practice, Vol. 48, No. 4, 10.04.2019, p. 216-219.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Paracetamol allergy in clinical practice

AU - Thompson, Grace

AU - Bundell, Christine

AU - Lucas, Michaela

PY - 2019/4/10

Y1 - 2019/4/10

N2 - Background: Paracetamol is a widely used analgesic to which hypersensitivity reactions are rare. Reactions to paracetamol May be due to the pharmacological effects of cyclooxygenase-1 inhibition or, more rarely, due to a selective allergy against paracetamol.Objective: This article aims to review the current literature in the context of two cases seen in the authors' allergy practice.Discussion: Paracetamol allergy is uncommon and, as a result, May be overlooked as a cause for immediate hypersensitivity, which can lead to a significant delay in diagnosis. Currently, specialist referral for a supervised oral challenge is required for formal diagnosis.

AB - Background: Paracetamol is a widely used analgesic to which hypersensitivity reactions are rare. Reactions to paracetamol May be due to the pharmacological effects of cyclooxygenase-1 inhibition or, more rarely, due to a selective allergy against paracetamol.Objective: This article aims to review the current literature in the context of two cases seen in the authors' allergy practice.Discussion: Paracetamol allergy is uncommon and, as a result, May be overlooked as a cause for immediate hypersensitivity, which can lead to a significant delay in diagnosis. Currently, specialist referral for a supervised oral challenge is required for formal diagnosis.

M3 - Review article

VL - 48

SP - 216

EP - 219

JO - Australian journal of general practice

JF - Australian journal of general practice

SN - 2208-794X

IS - 4

ER -