TY - JOUR
T1 - Outcomes of interventions in neonatal sepsis
T2 - A systematic review of qualitative research
AU - Taneri, Petek Eylul
AU - Devane, Declan
AU - Kirkham, Jamie
AU - Molloy, Eleanor
AU - Daly, Mandy
AU - Branagan, Aoife
AU - Suguitani, Denise
AU - Wynn, James L.
AU - Kissoon, Niranjan
AU - Kawaza, Kondwani
AU - Simons, Sinno H.P.
AU - Bonnard, Lívia Nagy
AU - Giannoni, Eric
AU - Strunk, Tobias
AU - Ohaja, Magdalena
AU - Mugabe, Kenneth
AU - Quirke, Fiona
AU - Bazilio, Kateregga
AU - Biesty, Linda
N1 - Publisher Copyright:
© 2024 The Author(s). International Journal of Gynecology & Obstetrics published by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.
PY - 2024/11
Y1 - 2024/11
N2 - Background: While a systematic review exists detailing neonatal sepsis outcomes from clinical trials, there remains an absence of a qualitative systematic review capturing the perspectives of key stakeholders. Objectives: Our aim is to identify outcomes from qualitative research on any intervention to prevent or improve the outcomes of neonatal sepsis that are important to parents, other family members, healthcare providers, policymakers, and researchers as a part of the development of a core outcome set (COS) for neonatal sepsis. Search Strategy: A literature search was carried out using MEDLINE, EMBASE, CINAHL, and PsycInfo databases. Selection Criteria: Publications describing qualitative data relating to neonatal sepsis outcomes were included. Data Collection and Analysis: Drawing on the concepts of thematic synthesis, texts related to outcomes were coded and grouped. These outcomes were then mapped to the domain headings of an existing model. Main Results: Out of 6777 records screened, six studies were included. Overall, 19 outcomes were extracted from the included studies. The most frequently reported outcomes were those in the domains related to parents, healthcare workers and individual organ systemas such as gastrointestinal system. The remaining outcomes were classified under the headings of general outcomes, miscellaneous outcomes, survival, and infection. Conclusions: The outcomes identified in this review are different from those reported in neonatal sepsis clinical trials, thus highlighting the importance of incorporating qualitative studies into COS development to encapsulate all relevant stakeholders' perspectives.
AB - Background: While a systematic review exists detailing neonatal sepsis outcomes from clinical trials, there remains an absence of a qualitative systematic review capturing the perspectives of key stakeholders. Objectives: Our aim is to identify outcomes from qualitative research on any intervention to prevent or improve the outcomes of neonatal sepsis that are important to parents, other family members, healthcare providers, policymakers, and researchers as a part of the development of a core outcome set (COS) for neonatal sepsis. Search Strategy: A literature search was carried out using MEDLINE, EMBASE, CINAHL, and PsycInfo databases. Selection Criteria: Publications describing qualitative data relating to neonatal sepsis outcomes were included. Data Collection and Analysis: Drawing on the concepts of thematic synthesis, texts related to outcomes were coded and grouped. These outcomes were then mapped to the domain headings of an existing model. Main Results: Out of 6777 records screened, six studies were included. Overall, 19 outcomes were extracted from the included studies. The most frequently reported outcomes were those in the domains related to parents, healthcare workers and individual organ systemas such as gastrointestinal system. The remaining outcomes were classified under the headings of general outcomes, miscellaneous outcomes, survival, and infection. Conclusions: The outcomes identified in this review are different from those reported in neonatal sepsis clinical trials, thus highlighting the importance of incorporating qualitative studies into COS development to encapsulate all relevant stakeholders' perspectives.
KW - core outcome set
KW - infant
KW - infectous disease
KW - neonatal sepsis
KW - newborn
KW - qualitative research
KW - qualitative systematic review
UR - http://www.scopus.com/inward/record.url?scp=85195315675&partnerID=8YFLogxK
U2 - 10.1002/ijgo.15725
DO - 10.1002/ijgo.15725
M3 - Review article
C2 - 38842248
AN - SCOPUS:85195315675
SN - 0020-7292
VL - 167
SP - 547
EP - 555
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - 2
ER -