Oral contraception does not alter typical post-exercise interleukin-6 and hepcidin levels in females

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Abstract

© 2013 Sports Medicine Australia. Objectives: The post-exercise interleukin-6 (IL-6) and hepcidin response was investigated during the hormone-deplete and hormone-replete phases of an estradiol and progestogen regulated oral contraceptive cycle (OCC). Design: Counterbalanced, repeated measures cross-over study. Methods: Ten active female monophasic oral contraceptive pill (OCP) users completed two 40min treadmill running trials at 75% of their pre-determined peak oxygen uptake velocity (vVO2peak). These trials were randomly performed in two specific phases of the OCC: (a) Day 2-4, representing a hormone-free withdrawal period (D-0); (b) Day 12-14, representing the end of the first week of active hormone therapy (D+7). Venous blood samples were drawn pre-, post- and 3h post-exercise. Results: In both trials, serum IL-6 was significantly elevated (p
Original languageEnglish
Pages (from-to)8-12
JournalJournal of Science and Medicine in Sport
Volume18
Issue number1
DOIs
Publication statusPublished - 2015

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