TY - JOUR
T1 - Oral contraception does not alter typical post-exercise interleukin-6 and hepcidin levels in females
AU - Sim, Marc
AU - Dawson, Brian
AU - Landers, Grant
AU - Swinkels, D.W.
AU - Tjalsma, H.
AU - Yeap, Bu
AU - Trinder, Debbie
AU - Peeling, Peter
PY - 2015
Y1 - 2015
N2 - © 2013 Sports Medicine Australia. Objectives: The post-exercise interleukin-6 (IL-6) and hepcidin response was investigated during the hormone-deplete and hormone-replete phases of an estradiol and progestogen regulated oral contraceptive cycle (OCC). Design: Counterbalanced, repeated measures cross-over study. Methods: Ten active female monophasic oral contraceptive pill (OCP) users completed two 40min treadmill running trials at 75% of their pre-determined peak oxygen uptake velocity (vVO2peak). These trials were randomly performed in two specific phases of the OCC: (a) Day 2-4, representing a hormone-free withdrawal period (D-0); (b) Day 12-14, representing the end of the first week of active hormone therapy (D+7). Venous blood samples were drawn pre-, post- and 3h post-exercise. Results: In both trials, serum IL-6 was significantly elevated (p
AB - © 2013 Sports Medicine Australia. Objectives: The post-exercise interleukin-6 (IL-6) and hepcidin response was investigated during the hormone-deplete and hormone-replete phases of an estradiol and progestogen regulated oral contraceptive cycle (OCC). Design: Counterbalanced, repeated measures cross-over study. Methods: Ten active female monophasic oral contraceptive pill (OCP) users completed two 40min treadmill running trials at 75% of their pre-determined peak oxygen uptake velocity (vVO2peak). These trials were randomly performed in two specific phases of the OCC: (a) Day 2-4, representing a hormone-free withdrawal period (D-0); (b) Day 12-14, representing the end of the first week of active hormone therapy (D+7). Venous blood samples were drawn pre-, post- and 3h post-exercise. Results: In both trials, serum IL-6 was significantly elevated (p
U2 - 10.1016/j.jsams.2013.11.008
DO - 10.1016/j.jsams.2013.11.008
M3 - Article
C2 - 24373771
VL - 18
SP - 8
EP - 12
JO - Journal of Science and Medicine in Sport
JF - Journal of Science and Medicine in Sport
SN - 1440-2440
IS - 1
ER -