This PhD thesis addresses several key questions on malignant pleural effusion (MPE), and mesothelioma management, providing novel, high-quality data to support improvements in patient care. The major findings include: 1) Breathlessness in MPE is likely contributed by abnormal diaphragmatic function; 2) Degree of breathlessness independently correlates with survival in patients with MPE; 3) In cases of individuals with MPE treated with an indwelling pleural catheter, symptom-guided drainage is as effective controlling breathlessness, without the burden and cost of daily drainage; 4) Cytological diagnosis of mesothelioma established from pleural fluid can avoid the need for invasive intervention of pleural tissue biopsy.
|Qualification||Doctor of Philosophy|
|Award date||7 Jul 2021|
|Publication status||Unpublished - 2021|