Optimising care of individuals with malignant pleural effusion

Sanjeevan Muruganandan

Research output: ThesisDoctoral Thesis

89 Downloads (Pure)


This PhD thesis addresses several key questions on malignant pleural effusion (MPE), and mesothelioma management, providing novel, high-quality data to support improvements in patient care. The major findings include: 1) Breathlessness in MPE is likely contributed by abnormal diaphragmatic function; 2) Degree of breathlessness independently correlates with survival in patients with MPE; 3) In cases of individuals with MPE treated with an indwelling pleural catheter, symptom-guided drainage is as effective controlling breathlessness, without the burden and cost of daily drainage; 4) Cytological diagnosis of mesothelioma established from pleural fluid can avoid the need for invasive intervention of pleural tissue biopsy.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
  • Lee, Gary, Supervisor
  • Creaney, Jenette, Supervisor
Thesis sponsors
Award date7 Jul 2021
Publication statusUnpublished - 2021


Dive into the research topics of 'Optimising care of individuals with malignant pleural effusion'. Together they form a unique fingerprint.

Cite this