Opportunistic detection of anal intraepithelial neoplasia at colonoscopy

Clara M. Forbes; Jenny McCloskey; Geoffrey M. Forbes

doi:10.1002/jgh3.12424

Opportunistic detection of anal intraepithelial neoplasia at colonoscopy

Clara M. Forbes, Jenny McCloskey, Geoffrey M. Forbes

Research output: Contribution to journal › Article › peer-review

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Abstract

Background and Aim: Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy. Methods: A retrospective review of a community-based practice for 2 years until December 2019 was conducted. Results: A total of 2525 patients (1051 males and 1474 females; median age 59 years) had 2608 colonoscopies. Ten patients (two males and eight females; median age 57.5 years) had incidentally detected AIN (condyloma acuminatum or AIN1, n = 4; AIN2 or 3, n = 6). AIN was detected in 1 of 261 (95% CI 1/142–1/480) colonoscopies and 1 of 163 (95% CI 1/83–1/321) colonoscopies in women over 40 years old. Conclusions: Opportunistically detecting AIN, especially in women over 40 years old, should be an important adjunct to colonoscopy-based colorectal neoplasia detection.

Original language	English
Pages (from-to)	1207-1210
Number of pages	4
Journal	JGH Open
Volume	4
Issue number	6
Early online date	14 Oct 2020
DOIs	https://doi.org/10.1002/jgh3.12424
Publication status	Published - Dec 2020

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title = "Opportunistic detection of anal intraepithelial neoplasia at colonoscopy",

abstract = "Background and Aim: Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy. Methods: A retrospective review of a community-based practice for 2 years until December 2019 was conducted. Results: A total of 2525 patients (1051 males and 1474 females; median age 59 years) had 2608 colonoscopies. Ten patients (two males and eight females; median age 57.5 years) had incidentally detected AIN (condyloma acuminatum or AIN1, n = 4; AIN2 or 3, n = 6). AIN was detected in 1 of 261 (95% CI 1/142–1/480) colonoscopies and 1 of 163 (95% CI 1/83–1/321) colonoscopies in women over 40 years old. Conclusions: Opportunistically detecting AIN, especially in women over 40 years old, should be an important adjunct to colonoscopy-based colorectal neoplasia detection.",

keywords = "anal intraepithelial neoplasia, colonoscopy, detection, human papilloma virus",

author = "Forbes, {Clara M.} and Jenny McCloskey and Forbes, {Geoffrey M.}",

year = "2020",

month = dec,

doi = "10.1002/jgh3.12424",

language = "English",

volume = "4",

pages = "1207--1210",

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issn = "2397-9070",

publisher = "John Wiley & Sons",

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TY - JOUR

T1 - Opportunistic detection of anal intraepithelial neoplasia at colonoscopy

AU - Forbes, Clara M.

AU - McCloskey, Jenny

AU - Forbes, Geoffrey M.

PY - 2020/12

Y1 - 2020/12

N2 - Background and Aim: Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy. Methods: A retrospective review of a community-based practice for 2 years until December 2019 was conducted. Results: A total of 2525 patients (1051 males and 1474 females; median age 59 years) had 2608 colonoscopies. Ten patients (two males and eight females; median age 57.5 years) had incidentally detected AIN (condyloma acuminatum or AIN1, n = 4; AIN2 or 3, n = 6). AIN was detected in 1 of 261 (95% CI 1/142–1/480) colonoscopies and 1 of 163 (95% CI 1/83–1/321) colonoscopies in women over 40 years old. Conclusions: Opportunistically detecting AIN, especially in women over 40 years old, should be an important adjunct to colonoscopy-based colorectal neoplasia detection.

AB - Background and Aim: Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy. Methods: A retrospective review of a community-based practice for 2 years until December 2019 was conducted. Results: A total of 2525 patients (1051 males and 1474 females; median age 59 years) had 2608 colonoscopies. Ten patients (two males and eight females; median age 57.5 years) had incidentally detected AIN (condyloma acuminatum or AIN1, n = 4; AIN2 or 3, n = 6). AIN was detected in 1 of 261 (95% CI 1/142–1/480) colonoscopies and 1 of 163 (95% CI 1/83–1/321) colonoscopies in women over 40 years old. Conclusions: Opportunistically detecting AIN, especially in women over 40 years old, should be an important adjunct to colonoscopy-based colorectal neoplasia detection.

KW - anal intraepithelial neoplasia

KW - colonoscopy

KW - detection

KW - human papilloma virus

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DO - 10.1002/jgh3.12424

M3 - Article

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SN - 2397-9070

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SP - 1207

EP - 1210

JO - JGH Open

JF - JGH Open

IS - 6

ER -

Opportunistic detection of anal intraepithelial neoplasia at colonoscopy

Abstract

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