Olfactory episodic memory as a predictor of pre-clinical dementia in healthy aging older adults

Rasangi Seneviratne

Research output: ThesisDoctoral Thesis

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Abstract

This thesis examined the predictive utility of olfactory episodic memory in the early detection of proxies for dementia using the newly developed Western Australia Olfactory Memory Test (WAOMT) in a sample of healthy aging older adults. The first study established WAOMT reliability and validity properties. In the second study, WAOMT recall predicted future changes in regional glucose metabolism in the pre-frontal cortex. In the final study, WAOMT performance was associated with baseline complex daily functioning, but not future daily functioning. In conclusion, the WAOMT is a reliable and valid tool to detect pre-clinical changes in healthy aging cohorts.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Weinborn, Michael, Supervisor
  • Sohrabi, Hamid, Supervisor
  • Badcock, David, Supervisor
  • Martins, Ralph, Supervisor
Thesis sponsors
Award date6 Jun 2022
DOIs
Publication statusUnpublished - 2021

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