Of mice and man: Differential DNMT dependence in mammalian ESCs

Ozren Bogdanović; Ryan Lister

doi:10.1016/j.stem.2015.04.009

Of mice and man: Differential DNMT dependence in mammalian ESCs

Ozren Bogdanović, Ryan Lister

Research output: Contribution to journal › Review article

2 Citations (Scopus)

Abstract

© 2015 Elsevier Inc. Liao et al. (2015) recently reported on the effects of disrupting DNA methyltransferase activity in human embryonic stem cells (hESCs). This work highlights key differences between mammalian ESC models upon the loss of these essential proteins and provides comprehensive base resolution methylome maps of DNMT targets during human development.

Original language	English
Pages (from-to)	459-460
Journal	Cell Stem Cell
Volume	16
Issue number	5
DOIs	https://doi.org/10.1016/j.stem.2015.04.009
Publication status	Published - 2015

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10.1016/j.stem.2015.04.009

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title = "Of mice and man: Differential DNMT dependence in mammalian ESCs",

abstract = "{\textcopyright} 2015 Elsevier Inc. Liao et al. (2015) recently reported on the effects of disrupting DNA methyltransferase activity in human embryonic stem cells (hESCs). This work highlights key differences between mammalian ESC models upon the loss of these essential proteins and provides comprehensive base resolution methylome maps of DNMT targets during human development.",

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T1 - Of mice and man: Differential DNMT dependence in mammalian ESCs

AU - Bogdanović, Ozren

AU - Lister, Ryan

PY - 2015

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AB - © 2015 Elsevier Inc. Liao et al. (2015) recently reported on the effects of disrupting DNA methyltransferase activity in human embryonic stem cells (hESCs). This work highlights key differences between mammalian ESC models upon the loss of these essential proteins and provides comprehensive base resolution methylome maps of DNMT targets during human development.

U2 - 10.1016/j.stem.2015.04.009

DO - 10.1016/j.stem.2015.04.009

M3 - Review article

C2 - 25957900

SN - 1934-5909

VL - 16

SP - 459

EP - 460

JO - Cell Stem Cell

JF - Cell Stem Cell

IS - 5

ER -

Of mice and man: Differential DNMT dependence in mammalian ESCs

Abstract

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