OCT angiography by absolute intensity difference applied to normal and diseased human retinas

Daniel Ruminski; Bartosz L. Sikorski; Danuta Bukowska; Maciej Szkulmowski; Krzysztof Krawiec; Grazyna Malukiewicz; Lech Bieganowski; Maciej Wojtkowski

doi:10.1364/BOE.6.002738

OCT angiography by absolute intensity difference applied to normal and diseased human retinas

Daniel Ruminski, Bartosz L. Sikorski, Danuta Bukowska, Maciej Szkulmowski, Krzysztof Krawiec, Grazyna Malukiewicz, Lech Bieganowski, Maciej Wojtkowski

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-tonoise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and eyes with diabetic maculopathy and branch retinal vein occlusion.

Original language	English
Pages (from-to)	2738-2754
Number of pages	17
Journal	Biomedical Optics Express
Volume	6
Issue number	8
DOIs	https://doi.org/10.1364/BOE.6.002738
Publication status	Published - 6 Jul 2015
Externally published	Yes

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10.1364/BOE.6.002738

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abstract = "We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-tonoise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and eyes with diabetic maculopathy and branch retinal vein occlusion.",

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AU - Ruminski, Daniel

AU - Sikorski, Bartosz L.

AU - Bukowska, Danuta

AU - Szkulmowski, Maciej

AU - Krawiec, Krzysztof

AU - Malukiewicz, Grazyna

AU - Bieganowski, Lech

AU - Wojtkowski, Maciej

PY - 2015/7/6

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N2 - We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-tonoise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and eyes with diabetic maculopathy and branch retinal vein occlusion.

AB - We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-tonoise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and eyes with diabetic maculopathy and branch retinal vein occlusion.

KW - Flow diagnostics

KW - Medical and biological imaging

KW - Ophthalmology

KW - Optical coherence tomography

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OCT angiography by absolute intensity difference applied to normal and diseased human retinas

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