OCT angiography by absolute intensity difference applied to normal and diseased human retinas

Daniel Ruminski, Bartosz L. Sikorski, Danuta Bukowska, Maciej Szkulmowski, Krzysztof Krawiec, Grazyna Malukiewicz, Lech Bieganowski, Maciej Wojtkowski

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-tonoise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and eyes with diabetic maculopathy and branch retinal vein occlusion.

Original languageEnglish
Pages (from-to)2738-2754
Number of pages17
JournalBiomedical Optics Express
Volume6
Issue number8
DOIs
Publication statusPublished - 6 Jul 2015
Externally publishedYes

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