Objective Auditory Measures in Individuals at High Risk of Alzheimer’s disease: Implications for Early Detection

Hadeel Tarawneh

doi:10.26182/2b5b-5y61

Objective Auditory Measures in Individuals at High Risk of Alzheimer’s disease: Implications for Early Detection

Hadeel Tarawneh

Research output: Thesis › Doctoral Thesis

171 Downloads (Pure)

Abstract

Cognitive decline is strongly associated with peripheral hearing loss and changes in central auditory processing skills. Investigating auditory functions in populations at risk of developing AD using auditory electrophysiological measurements may provide a tool to aid the identification of preclinical AD. This thesis aimed to investigate auditory electrophysiological assessment measures in relation to biological markers of AD in those at high risk of AD. This thesis also investigated the relatability of objective electrophysiological measures (auditory steady-state response) for measuring hearing thresholds in older adults and how it compares to the current gold standard, hearing acuity test(behavioural pure-tone audiometry).

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Jayakody, Dona, Supervisor Mulders, Wilhelmina, Supervisor Sohrabi, Hamid, Supervisor Martins, Ralph, Supervisor
Thesis sponsors	Australian Government Research Training Program
Award date	17 Apr 2023
DOIs	https://doi.org/10.26182/2b5b-5y61
Publication status	Unpublished - 2022

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10.26182/2b5b-5y61

THESIS - DOCTOR OF PHILOSOPHY - TARAWNEH Hadeel - 2023
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3 Review article
2 Article

Auditory Event-Related Potentials in Older Adults with Subjective Memory Complaints
Tarawneh, H., Jayakody, D., Verma, S., Dore, V., Xia, Y., Mulders, W., Martins, R. & Sohrabi, H., 2023, In: Journal of Alzheimer's Disease. 92, 3, p. 1093-1109 17 p.
Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)
Comparison of Auditory Steady-State Responses with conventional audiometry in Older Adults
Tarawneh, H., Sohrabi, H., Mulders, W., Martins, R. & Jayakody, D., 4 Jul 2022, In: Frontiers in Neurology. 13, 924096.
Research output: Contribution to journal › Review article › peer-review

Open Access

4 Citations (Scopus)
Understanding the relationship between age-related hearing loss and Alzheimer’s disease: A Narrative Review
Tarawneh, H., Jayakody, D., Sohrabi, H., Martins, R. & Mulders, W., 6 Sept 2022, In: Journal of Alzheimer's Disease Reports. 6, 1, p. 539-556 18 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
17 Citations (Scopus)

Cite this

@phdthesis{6cc54910bfa24a2d9d7e294afba4d315,

title = "Objective Auditory Measures in Individuals at High Risk of Alzheimer{\textquoteright}s disease: Implications for Early Detection",

abstract = "Cognitive decline is strongly associated with peripheral hearing loss and changes in central auditory processing skills. Investigating auditory functions in populations at risk of developing AD using auditory electrophysiological measurements may provide a tool to aid the identification of preclinical AD. This thesis aimed to investigate auditory electrophysiological assessment measures in relation to biological markers of AD in those at high risk of AD. This thesis also investigated the relatability of objective electrophysiological measures (auditory steady-state response) for measuring hearing thresholds in older adults and how it compares to the current gold standard, hearing acuity test(behavioural pure-tone audiometry).",

keywords = "Alzheimer{\textquoteright}s disease, Cognitive function, Event-related potentials, Auditory steady-state response (ASSR), Hearing, Objective audiometry, Older adult",

author = "Hadeel Tarawneh",

year = "2022",

doi = "10.26182/2b5b-5y61",

language = "English",

school = "The University of Western Australia",

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TY - BOOK

T1 - Objective Auditory Measures in Individuals at High Risk of Alzheimer’s disease: Implications for Early Detection

AU - Tarawneh, Hadeel

PY - 2022

Y1 - 2022

N2 - Cognitive decline is strongly associated with peripheral hearing loss and changes in central auditory processing skills. Investigating auditory functions in populations at risk of developing AD using auditory electrophysiological measurements may provide a tool to aid the identification of preclinical AD. This thesis aimed to investigate auditory electrophysiological assessment measures in relation to biological markers of AD in those at high risk of AD. This thesis also investigated the relatability of objective electrophysiological measures (auditory steady-state response) for measuring hearing thresholds in older adults and how it compares to the current gold standard, hearing acuity test(behavioural pure-tone audiometry).

AB - Cognitive decline is strongly associated with peripheral hearing loss and changes in central auditory processing skills. Investigating auditory functions in populations at risk of developing AD using auditory electrophysiological measurements may provide a tool to aid the identification of preclinical AD. This thesis aimed to investigate auditory electrophysiological assessment measures in relation to biological markers of AD in those at high risk of AD. This thesis also investigated the relatability of objective electrophysiological measures (auditory steady-state response) for measuring hearing thresholds in older adults and how it compares to the current gold standard, hearing acuity test(behavioural pure-tone audiometry).

KW - Alzheimer’s disease

KW - Cognitive function

KW - Event-related potentials

KW - Auditory steady-state response (ASSR)

KW - Hearing

KW - Objective audiometry

KW - Older adult

U2 - 10.26182/2b5b-5y61

DO - 10.26182/2b5b-5y61

M3 - Doctoral Thesis

ER -

Objective Auditory Measures in Individuals at High Risk of Alzheimer’s disease: Implications for Early Detection

Abstract

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Research output

Auditory Event-Related Potentials in Older Adults with Subjective Memory Complaints

Comparison of Auditory Steady-State Responses with conventional audiometry in Older Adults

Understanding the relationship between age-related hearing loss and Alzheimer’s disease: A Narrative Review

Cite this