TY - JOUR
T1 - Obesity in patients without diabetes undergoing coronary artery bypass graft surgery
T2 - Time to select patients for semaglutide
AU - Lan, Nick S R
AU - Ali, Umar S
AU - Larbalestier, Robert
AU - Dwivedi, Girish
AU - Fegan, P Gerry
N1 - Copyright © 2024 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.
PY - 2024/1
Y1 - 2024/1
N2 - Patients undergoing coronary artery bypass graft (CABG) surgery require intensive secondary prevention. Semaglutide reduced cardiovascular events in patients with cardiovascular disease and overweight or obesity but without diabetes in the SELECT trial. In this real-world study of 1386 patients without diabetes undergoing CABG surgery in an Australian hospital, approximately 1 in 2 patients (53.3 %) were potentially eligible for semaglutide based on the SELECT trial criteria. These findings highlight that a significant percentage of this very high-risk cohort merit receiving semaglutide for weight management and cardiovascular risk reduction. The implications for optimal care, healthcare costs and clinical guidelines require further evaluation.
AB - Patients undergoing coronary artery bypass graft (CABG) surgery require intensive secondary prevention. Semaglutide reduced cardiovascular events in patients with cardiovascular disease and overweight or obesity but without diabetes in the SELECT trial. In this real-world study of 1386 patients without diabetes undergoing CABG surgery in an Australian hospital, approximately 1 in 2 patients (53.3 %) were potentially eligible for semaglutide based on the SELECT trial criteria. These findings highlight that a significant percentage of this very high-risk cohort merit receiving semaglutide for weight management and cardiovascular risk reduction. The implications for optimal care, healthcare costs and clinical guidelines require further evaluation.
U2 - 10.1016/j.orcp.2024.02.001
DO - 10.1016/j.orcp.2024.02.001
M3 - Letter
C2 - 38331597
SN - 1871-403X
VL - 18
SP - 76
EP - 78
JO - Obesity Research & Clinical Practice
JF - Obesity Research & Clinical Practice
IS - 1
ER -