Nutritional diets accelerate amyloid beta metabolism and prevent the induction of chronic diseases and Alzheimer’s disease

Research output: Contribution to conferenceAbstract

Abstract


The First Invited Notable (Principal Research Fellow) Speaker at the PLENARY FORUM at the 4th Annual Global Health Conference-2016, Kaohsiung, Taiwan. Plenary Forum Presentation Attached as Conference Presentation, Title: Nutritional diets accelerate amyloid beta metabolism and prevent the induction of chronic diseases and Alzheimer’s disease. This ORAL presentation at the AGHC-2016 is related to the scholarly publication in PHOTON but differ with relevance to the International Agency for Standards recognition of the written publication that is associated with the Richard Kuhn Research Award-2015 (Endocrinology and Metabolism) presented to Ian James Martins. ABSTRACT The inductions of chronic diseases and neurodegeneration have become a major concern in various countries in the developed and developing world. Central co-ordination and homeostasis of neuroendocrine systems and renin-angiotensin systems (RAS) are influenced by external stressors, diet and lifestyles that lead to abnormal nitric oxide and neural pathways, appetite dysregulation and organ disease. The alteration in circadian photic signals in the neuroendocrine system involve the hypothalamus and the suprachiasmatic nucleus that are linked to apelinergic dysregulation associated with appetite disorders and various organ diseases. The peripheral sink amyloid beta hypothesis indicates that amyloid beta (Aβ) is rapidly removed by the liver and chronic diseases are connected to apelinergic dysfunction with abnormal amyloidogenic pathways. Environmental pollutants associated with unhealthy nutritional habits increase xenobiotics in plasma and may further promote neuroendocrine disease, kidney disease and non alcoholic fatty liver disease (NAFLD) with poor Aβ metabolism. Furthermore stress and unhealthy nutritional lifestyles increase oxidative stress with abnormal apelin and RAS regulation associated with poor nitric oxide and vascular Aβ metabolism with the acceleration of neuroendocrine diseases that include obesity, diabetes, cardiovascular disease and neurodegenerative diseases
Original languageEnglish
Publication statusPublished - 18 Nov 2018
Event4th Annual Global Health Conference-2016 - Kaohshiung, Taiwan, Province of China
Duration: 18 Nov 201620 Nov 2016

Conference

Conference4th Annual Global Health Conference-2016
CountryTaiwan, Province of China
CityKaohshiung
Period18/11/1620/11/16

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    Martins, I. (2018). Nutritional diets accelerate amyloid beta metabolism and prevent the induction of chronic diseases and Alzheimer’s disease. Abstract from 4th Annual Global Health Conference-2016, Kaohshiung, Taiwan, Province of China.