We aimed to review nutritional benefits of probiotics in preterm infants considering increased risk of long-term growth and neurodevelopmental impairment following suboptimal nutrition in early postnatal life . The results of our systematic reviews and randomised controlled trial indicated that probiotics improved feeding tolerance and short-term weight-gain in preterm infants. Both single-strain and combination of probiotics had comparable efficacy in reducing time to full feeds and gut dysbiosis in extremely preterm infants. Further research is needed to confirm clinical benefits of specific strains of probiotics and in probiotic supplementation in preterm small for gestational age infants.
Original language | English |
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Qualification | Doctor of Philosophy |
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Awarding Institution | - The University of Western Australia
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Supervisors/Advisors | - Simmer, Karen, Supervisor
- Patole, Sanjay, Supervisor
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Award date | 31 Aug 2022 |
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DOIs | |
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Publication status | Unpublished - 2022 |
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