Nutritional approaches for the primary prevention of allergic disease: An update

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

The dramatic rise in early childhood allergic diseases indicates the specific vulnerability of the immune system to early life environmental changes. Dietary changes are at the centre of lifestyle changes that underpin many modern inflammatory and metabolic diseases, and therefore are an essential element of prevention strategies. Although modern dietary changes are complex and involve changing patterns of many nutrients, there is also an interest in the early life effects of specific nutrients including polyunsaturated fatty acids, oligosaccharides (soluble fibre), antioxidants, folate and other vitamins that have documented effects on immune function as well as metabolism. A better understanding of nutritional programming of immune health, nutritional epigenetics and the biological processes sensitive to nutritional exposures in early life may lead to dietary strategies that provide more tolerogenic conditions during early immune programming and reduce the burden of many inflammatory diseases, not just allergy.
Original languageEnglish
Pages (from-to)962-969
Number of pages8
JournalJournal of Paediatrics and Child Health
Volume51
Issue number10
Early online date2 Jul 2015
DOIs
Publication statusPublished - Oct 2015

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