Nutrition Therapy Regulates Caffeine Metabolism with Relevance to NAFLD and Induction of Type 3 Diabetes

Ian Martins

Research output: Contribution to conferenceAbstractpeer-review


In the developed and developing world nutritional interventions have become essential to prevent global Non Alcoholic Fatty Liver Disease (NAFLD) and to maintain the metabolism of glucose/fatty acids that are linked to amyloid beta and xenobiotic metabolism. The World Health Organization (WHO) has reported that cardiovascular disease is the most prevalent global chronic disease that may be connected to NAFLD and the alarming death rate in various communities. Overeating may accelerate chronic diseases with repression of anti-aging genes linked to NAFLD and delayed caffeine clearance linked to the induction of Type 3 diabetes in global populations. Caffeine (appetite suppressant) may improve the adipose tissue-liver cross talk with the prevention of NAFLD in obese and Type 2 diabetic populations. Nutritional interventions to reverse NAFLD in the developing world are associated with accelerated caffeine clearance rates with prevention of caffeine induced mitochondrial apoptosis that is linked to early neuron loss and the development of Type 3 diabetes in these populations.
Original languageEnglish
Publication statusPublished - 25 Apr 2017
EventIst International Biotechnology Congress-2017 - Xian, China
Duration: 25 Apr 201727 Apr 2017


ConferenceIst International Biotechnology Congress-2017


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