Novel sulfoxide ligands for Rh-catalysed dddition reactions of organoboron nucleophiles

In this thesis, we introduce chiral sulfoxide ligands for transition metal catalysis.
Chapter 1 covers various aspects of catalysis, chirality and asymmetric synthesis employing chiral metal-ligand catalysts.
In chapter 2, a novel μ-OH bridged, S-chiral bissulfoxide rhodium complex is obtained and tested in rhodium catalysed additions of arylboroxines to N-tosylarylimines. Excellent selectivities and reactivities for a wide range of substrates were obtained with very low catalyst loadings under simple reaction conditions.
In chapter 3, we introduce a new bissulfoxide ligand with fluorine atoms in order to sterically and electronically tune it. Good reactivities and high selectivities were obtained for various addition reactions.