Abstract
In this thesis, we introduce chiral sulfoxide ligands for transition metal catalysis.
Chapter 1 covers various aspects of catalysis, chirality and asymmetric synthesis employing chiral metal-ligand catalysts.
In chapter 2, a novel μ-OH bridged, S-chiral bissulfoxide rhodium complex is obtained and tested in rhodium catalysed additions of arylboroxines to N-tosylarylimines. Excellent selectivities and reactivities for a wide range of substrates were obtained with very low catalyst loadings under simple reaction conditions.
In chapter 3, we introduce a new bissulfoxide ligand with fluorine atoms in order to sterically and electronically tune it. Good reactivities and high selectivities were obtained for various addition reactions.
Chapter 1 covers various aspects of catalysis, chirality and asymmetric synthesis employing chiral metal-ligand catalysts.
In chapter 2, a novel μ-OH bridged, S-chiral bissulfoxide rhodium complex is obtained and tested in rhodium catalysed additions of arylboroxines to N-tosylarylimines. Excellent selectivities and reactivities for a wide range of substrates were obtained with very low catalyst loadings under simple reaction conditions.
In chapter 3, we introduce a new bissulfoxide ligand with fluorine atoms in order to sterically and electronically tune it. Good reactivities and high selectivities were obtained for various addition reactions.
| Original language | English |
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| Qualification | Doctor of Philosophy |
| Awarding Institution |
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| Supervisors/Advisors |
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| Award date | 15 Feb 2017 |
| Publication status | Unpublished - 2016 |