Novel sulfoxide ligands for Rh-catalysed dddition reactions of organoboron nucleophiles

Guangzhen Zhao

Research output: ThesisDoctoral Thesis

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Abstract

In this thesis, we introduce chiral sulfoxide ligands for transition metal catalysis.
Chapter 1 covers various aspects of catalysis, chirality and asymmetric synthesis employing chiral metal-ligand catalysts.
In chapter 2, a novel μ-OH bridged, S-chiral bissulfoxide rhodium complex is obtained and tested in rhodium catalysed additions of arylboroxines to N-tosylarylimines. Excellent selectivities and reactivities for a wide range of substrates were obtained with very low catalyst loadings under simple reaction conditions.
In chapter 3, we introduce a new bissulfoxide ligand with fluorine atoms in order to sterically and electronically tune it. Good reactivities and high selectivities were obtained for various addition reactions.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Dorta, Reto, Supervisor
  • Koutsantonis, George, Supervisor
Award date15 Feb 2017
Publication statusUnpublished - 2016

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