Nonclinality of molecular variation implicates selection in maintaining a morphological cline of Drosophila melanogaster

J. Gockel, Jason Kennington, A. Hoffmann, D.B. Goldstein, L. Partridge

Research output: Contribution to journalArticle

93 Citations (Scopus)

Abstract

One general approach for assessing whether phenotypic variation is due to selection is to test its correlation with presumably neutral molecular variation. Neutral variation is determined by population history, the most likely alternative explanation of spatial genetic structure, whereas phenotypic variation may be influenced by the spatial pattern or selection pressure. Several methods for comparing the spatial apportionment of molecular and morphological variation have been used. Here, we present an analysis of variance framework that compares the magnitudes of latitudinal effects for molecular and morphological variation along a body size dine in Australian Drosophila populations. Explicit incorporation of the relevant. environmental gradient can result in a simple and powerful test of selection. For the Australian dine, our analysis provides strong internal evidence that the dine is due to selection.
Original languageEnglish
Pages (from-to)319-323
JournalGenetics
Volume158
Publication statusPublished - 2001

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