Non-immediate heparin and heparinoid cutaneous allergic reactions: a role for fondaparinux

Elina Tan; Grace Thompson; Charlotta Ekstrom; Michaela Lucas

doi:10.1111/imj.13659

Non-immediate heparin and heparinoid cutaneous allergic reactions: a role for fondaparinux

Elina Tan, Grace Thompson, Charlotta Ekstrom, Michaela Lucas

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Abstract

Non-immediate allergic cutaneous reactions to heparins have been increasingly reported, typically manifesting as large, eczematous plaques at sites of subcutaneous injection. Patients may demonstrate cross-reactivity between unfractionated heparin, low molecular weight heparin and semi-synthetic heparinoids, making finding an alternative difficult. Fondaparinux has been identified as a useful alternative in such patients; here we present the first two documented cases in Australia and a literature review.

Original language	English
Pages (from-to)	73-77
Number of pages	5
Journal	Internal Medicine Journal
Volume	48
Issue number	1
DOIs	https://doi.org/10.1111/imj.13659
Publication status	Published - 1 Jan 2018

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KW - hypersensitivity

KW - immunology

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KW - unfractionated heparin

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Non-immediate heparin and heparinoid cutaneous allergic reactions: a role for fondaparinux

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