Non-coding RNAs in Mammary Gland Development and Disease

  • Gurveen K Sandhu
  • , Michael J G Milevskiy
  • , Wesley Wilson
  • , Annette M Shewan
  • , Melissa A Brown

Research output: Chapter in Book/Conference paperChapterpeer-review

Abstract

Non-coding RNAs (ncRNAs) are untranslated RNA molecules that function to regulate the expression of numerous genes and associated biochemical pathways and cellular functions. NcRNAs include small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). They participate in the regulation of all developmental processes and are frequently aberrantly expressed or functionally defective in disease. This Chapter will focus on the role of ncRNAs, in particular miRNAs and lncRNAs, in mammary gland development and disease.

Original languageEnglish
Title of host publicationNon-coding RNA and the Reproductive System
EditorsDagmar Wilhelm, Pascal Bernard
Place of PublicationNetherlands
PublisherSpringer
Chapter7
Pages121-153
Number of pages33
ISBN (Electronic)9789401774178
ISBN (Print)9789401774154
DOIs
Publication statusPublished - 1 Jan 2016
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume886
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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