Non-coding RNAs in Mammary Gland Development and Disease

Gurveen K Sandhu, Michael J G Milevskiy, Wesley Wilson, Annette M Shewan, Melissa A Brown

Research output: Chapter in Book/Conference paperChapter

11 Citations (Scopus)

Abstract

Non-coding RNAs (ncRNAs) are untranslated RNA molecules that function to regulate the expression of numerous genes and associated biochemical pathways and cellular functions. NcRNAs include small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). They participate in the regulation of all developmental processes and are frequently aberrantly expressed or functionally defective in disease. This Chapter will focus on the role of ncRNAs, in particular miRNAs and lncRNAs, in mammary gland development and disease.

Original languageEnglish
Title of host publicationNon-coding RNA and the Reproductive System
EditorsDagmar Wilhelm, Pascal Bernard
Place of PublicationNetherlands
PublisherSpringer
Chapter7
Pages121-153
ISBN (Electronic)9789401774178
ISBN (Print)9789401774154
DOIs
Publication statusPublished - 2016
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
PublisherSpringer
Volume886
ISSN (Print)0065-2598

Fingerprint

Untranslated RNA
Breast Diseases
Human Mammary Glands
Long Noncoding RNA
MicroRNAs
Small Nucleolar RNA
Small Interfering RNA
RNA
Gene Expression

Cite this

Sandhu, G. K., Milevskiy, M. J. G., Wilson, W., Shewan, A. M., & Brown, M. A. (2016). Non-coding RNAs in Mammary Gland Development and Disease. In D. Wilhelm, & P. Bernard (Eds.), Non-coding RNA and the Reproductive System (pp. 121-153). (Advances in Experimental Medicine and Biology; Vol. 886). Netherlands: Springer. https://doi.org/10.1007/978-94-017-7417-8_7
Sandhu, Gurveen K ; Milevskiy, Michael J G ; Wilson, Wesley ; Shewan, Annette M ; Brown, Melissa A. / Non-coding RNAs in Mammary Gland Development and Disease. Non-coding RNA and the Reproductive System. editor / Dagmar Wilhelm ; Pascal Bernard. Netherlands : Springer, 2016. pp. 121-153 (Advances in Experimental Medicine and Biology).
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Sandhu, GK, Milevskiy, MJG, Wilson, W, Shewan, AM & Brown, MA 2016, Non-coding RNAs in Mammary Gland Development and Disease. in D Wilhelm & P Bernard (eds), Non-coding RNA and the Reproductive System. Advances in Experimental Medicine and Biology, vol. 886, Springer, Netherlands, pp. 121-153. https://doi.org/10.1007/978-94-017-7417-8_7

Non-coding RNAs in Mammary Gland Development and Disease. / Sandhu, Gurveen K; Milevskiy, Michael J G; Wilson, Wesley; Shewan, Annette M; Brown, Melissa A.

Non-coding RNA and the Reproductive System. ed. / Dagmar Wilhelm; Pascal Bernard. Netherlands : Springer, 2016. p. 121-153 (Advances in Experimental Medicine and Biology; Vol. 886).

Research output: Chapter in Book/Conference paperChapter

TY - CHAP

T1 - Non-coding RNAs in Mammary Gland Development and Disease

AU - Sandhu, Gurveen K

AU - Milevskiy, Michael J G

AU - Wilson, Wesley

AU - Shewan, Annette M

AU - Brown, Melissa A

PY - 2016

Y1 - 2016

N2 - Non-coding RNAs (ncRNAs) are untranslated RNA molecules that function to regulate the expression of numerous genes and associated biochemical pathways and cellular functions. NcRNAs include small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). They participate in the regulation of all developmental processes and are frequently aberrantly expressed or functionally defective in disease. This Chapter will focus on the role of ncRNAs, in particular miRNAs and lncRNAs, in mammary gland development and disease.

AB - Non-coding RNAs (ncRNAs) are untranslated RNA molecules that function to regulate the expression of numerous genes and associated biochemical pathways and cellular functions. NcRNAs include small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). They participate in the regulation of all developmental processes and are frequently aberrantly expressed or functionally defective in disease. This Chapter will focus on the role of ncRNAs, in particular miRNAs and lncRNAs, in mammary gland development and disease.

KW - Animals

KW - Breast Diseases/genetics

KW - Female

KW - Humans

KW - Mammary Glands, Animal/growth & development

KW - Mammary Glands, Human/growth & development

KW - RNA, Untranslated/genetics

U2 - 10.1007/978-94-017-7417-8_7

DO - 10.1007/978-94-017-7417-8_7

M3 - Chapter

SN - 9789401774154

T3 - Advances in Experimental Medicine and Biology

SP - 121

EP - 153

BT - Non-coding RNA and the Reproductive System

A2 - Wilhelm, Dagmar

A2 - Bernard, Pascal

PB - Springer

CY - Netherlands

ER -

Sandhu GK, Milevskiy MJG, Wilson W, Shewan AM, Brown MA. Non-coding RNAs in Mammary Gland Development and Disease. In Wilhelm D, Bernard P, editors, Non-coding RNA and the Reproductive System. Netherlands: Springer. 2016. p. 121-153. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-94-017-7417-8_7