Non-coding RNAs in Mammary Gland Development and Disease

Gurveen K Sandhu, Michael J G Milevskiy, Wesley Wilson, Annette M Shewan, Melissa A Brown

Research output: Chapter in Book/Conference paperChapter

14 Citations (Scopus)

Abstract

Non-coding RNAs (ncRNAs) are untranslated RNA molecules that function to regulate the expression of numerous genes and associated biochemical pathways and cellular functions. NcRNAs include small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). They participate in the regulation of all developmental processes and are frequently aberrantly expressed or functionally defective in disease. This Chapter will focus on the role of ncRNAs, in particular miRNAs and lncRNAs, in mammary gland development and disease.

Original languageEnglish
Title of host publicationNon-coding RNA and the Reproductive System
EditorsDagmar Wilhelm, Pascal Bernard
Place of PublicationNetherlands
PublisherSpringer
Chapter7
Pages121-153
ISBN (Electronic)9789401774178
ISBN (Print)9789401774154
DOIs
Publication statusPublished - 2016
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
PublisherSpringer
Volume886
ISSN (Print)0065-2598

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