We present a Nitche's method to couple non-conforming two and three-dimensional non uniform rational b-splines (NURBS) patches in the context of isogeometric analysis. We present results for linear elastostatics in two and and three-dimensions. The method can deal with surface-surface or volume-volume coupling, and we show how it can be used to handle heterogeneities such as inclusions. We also present preliminary results on modal analysis. This simple coupling method has the potential to increase the applicability of NURBS-based isogeometric analysis for practical applications.