Neuropsychiatric presentations and outcomes in children and adolescents with primary brain tumours: Systematic review

Yulia Zyrianova, L. Alexander, R. Faruqui

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

© 2016 Taylor & Francis Group, LLC. Objective: The purpose of this study was to systematically review the literature relating to the neuropsychiatric symptoms at presentation and outcome of childhood brain tumours.Methods: Seven online databases pertaining to the neuropsychiatric presentation and outcomes of childhood CNS tumours were searched and PRISMA guidelines were followed. Temporal limits were not applied to the searches.Results: There were 1879 relevant search results in total. After discovering the large body of both primary and secondary research in the field of cognitive and neuropsychological outcomes of brain tumours in children, these studies were excluded. Quality-of-life studies were excluded for the same reason. Thirty-one papers were chosen for discussion in this review.Conclusion: This timely systematic review concluded that neuropsychiatric presentations are common in children with CNS tumours-with the presence of behavioural and psychological symptoms in up to 57% of cases, their frequency varies according to age of onset and is strongly associated with time since diagnosis. The findings highlight the necessity for routine psychological and psychiatric screenings of children with suspected brain tumours and at follow-up and a number of clinical recommendations to this effect are listed.
Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalBrain Injury
Volume30
Issue number1
DOIs
Publication statusPublished - 2016

Fingerprint

Brain Neoplasms
Psychology
Behavioral Symptoms
Age of Onset
Psychiatry
Neoplasms
Quality of Life
Databases
Guidelines
Research
Systematic Review
Brain Tumor
Childhood
Psychological
Central Nervous System
Child Studies
Onset
Screening
Data Base

Cite this

@article{f2f1b45fbb9f47d0b38cae0e52542f86,
title = "Neuropsychiatric presentations and outcomes in children and adolescents with primary brain tumours: Systematic review",
abstract = "{\circledC} 2016 Taylor & Francis Group, LLC. Objective: The purpose of this study was to systematically review the literature relating to the neuropsychiatric symptoms at presentation and outcome of childhood brain tumours.Methods: Seven online databases pertaining to the neuropsychiatric presentation and outcomes of childhood CNS tumours were searched and PRISMA guidelines were followed. Temporal limits were not applied to the searches.Results: There were 1879 relevant search results in total. After discovering the large body of both primary and secondary research in the field of cognitive and neuropsychological outcomes of brain tumours in children, these studies were excluded. Quality-of-life studies were excluded for the same reason. Thirty-one papers were chosen for discussion in this review.Conclusion: This timely systematic review concluded that neuropsychiatric presentations are common in children with CNS tumours-with the presence of behavioural and psychological symptoms in up to 57{\%} of cases, their frequency varies according to age of onset and is strongly associated with time since diagnosis. The findings highlight the necessity for routine psychological and psychiatric screenings of children with suspected brain tumours and at follow-up and a number of clinical recommendations to this effect are listed.",
author = "Yulia Zyrianova and L. Alexander and R. Faruqui",
year = "2016",
doi = "10.3109/02699052.2015.1075590",
language = "English",
volume = "30",
pages = "1--9",
journal = "Brain Injury",
issn = "0269-9052",
publisher = "Taylor & Francis",
number = "1",

}

Neuropsychiatric presentations and outcomes in children and adolescents with primary brain tumours: Systematic review. / Zyrianova, Yulia; Alexander, L.; Faruqui, R.

In: Brain Injury, Vol. 30, No. 1, 2016, p. 1-9.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Neuropsychiatric presentations and outcomes in children and adolescents with primary brain tumours: Systematic review

AU - Zyrianova, Yulia

AU - Alexander, L.

AU - Faruqui, R.

PY - 2016

Y1 - 2016

N2 - © 2016 Taylor & Francis Group, LLC. Objective: The purpose of this study was to systematically review the literature relating to the neuropsychiatric symptoms at presentation and outcome of childhood brain tumours.Methods: Seven online databases pertaining to the neuropsychiatric presentation and outcomes of childhood CNS tumours were searched and PRISMA guidelines were followed. Temporal limits were not applied to the searches.Results: There were 1879 relevant search results in total. After discovering the large body of both primary and secondary research in the field of cognitive and neuropsychological outcomes of brain tumours in children, these studies were excluded. Quality-of-life studies were excluded for the same reason. Thirty-one papers were chosen for discussion in this review.Conclusion: This timely systematic review concluded that neuropsychiatric presentations are common in children with CNS tumours-with the presence of behavioural and psychological symptoms in up to 57% of cases, their frequency varies according to age of onset and is strongly associated with time since diagnosis. The findings highlight the necessity for routine psychological and psychiatric screenings of children with suspected brain tumours and at follow-up and a number of clinical recommendations to this effect are listed.

AB - © 2016 Taylor & Francis Group, LLC. Objective: The purpose of this study was to systematically review the literature relating to the neuropsychiatric symptoms at presentation and outcome of childhood brain tumours.Methods: Seven online databases pertaining to the neuropsychiatric presentation and outcomes of childhood CNS tumours were searched and PRISMA guidelines were followed. Temporal limits were not applied to the searches.Results: There were 1879 relevant search results in total. After discovering the large body of both primary and secondary research in the field of cognitive and neuropsychological outcomes of brain tumours in children, these studies were excluded. Quality-of-life studies were excluded for the same reason. Thirty-one papers were chosen for discussion in this review.Conclusion: This timely systematic review concluded that neuropsychiatric presentations are common in children with CNS tumours-with the presence of behavioural and psychological symptoms in up to 57% of cases, their frequency varies according to age of onset and is strongly associated with time since diagnosis. The findings highlight the necessity for routine psychological and psychiatric screenings of children with suspected brain tumours and at follow-up and a number of clinical recommendations to this effect are listed.

U2 - 10.3109/02699052.2015.1075590

DO - 10.3109/02699052.2015.1075590

M3 - Review article

VL - 30

SP - 1

EP - 9

JO - Brain Injury

JF - Brain Injury

SN - 0269-9052

IS - 1

ER -