Neural field theory: Exploring topographic organisation and re-organisation of neural circuitry

Nicholas Michael Gale

Research output: ThesisMaster's Thesis

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Abstract

This thesis will explore topographic organisation in the context of field theory. In the first instance it will be shown that spike­timing-dependent plasticity in conjunction with spatio-temporally correlated activity can support topographic organisation (or re-organisation). This result is important because it is known that the activity that drives organisation in development is in the form of spatio-temporally correlated waves. The model is computationally analysed .and shown to support planar/radial wave refinement, noise tolerance, direction selectivity, and refinement of ectopic projections. These results inform interpretation of current data showing topographic error correction of ephrinA2A5 mice using magnetic stimulation.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Thesis sponsors
Award date13 Nov 2018
DOIs
Publication statusUnpublished - 2018

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