Needle-based refractive index measurement using low-coherence interferometry

AM Zysk, SG Adie, JJ Armstrong, MS Leigh, A Paduch, David Sampson, FT Nguyen, SA Boppart

    Research output: Contribution to journalArticlepeer-review

    53 Citations (Scopus)

    Abstract

    We present a novel needle-based device for the measurement of refractive index and scattering using low-coherence interferometry. Coupled to the sample arm of an optical coherence tomography system, the device detects the scattering response of, and optical path length through, a sample residing in a fixed-width channel. We report use of the device to make near-infrared measurements of tissues and materials with known optical properties. The device could be used to exploit the refractive index variations of tissue for medical and biological diagnostics accessible by needle insertion.
    Original languageEnglish
    Pages (from-to)385-387
    JournalOptics Letters
    Volume32
    Issue number4
    DOIs
    Publication statusPublished - 2007

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