Near Video-Rate Optical Coherence Elastography by Acceleration With a Graphics Processing Unit

Rodney Kirk; Brendan Kennedy; David Sampson; Robert Mclaughlin

doi:10.1109/JLT.2015.2413402

Near Video-Rate Optical Coherence Elastography by Acceleration With a Graphics Processing Unit

Rodney Kirk, Brendan Kennedy, David Sampson, Robert Mclaughlin

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Abstract

© 2015 IEEE. We present a graphics processing unit (GPU)-accelerated optical coherence elastography (OCE) system capable of generating strain images (elastograms) of soft tissue at near video-rates. The system implements phase-sensitive compression OCE using a pipeline of GPU kernel functions to enable a highly parallel implementation of OCE processing using the OpenCL framework. Developed on a commercial-grade GPU and desktop computer, the system achieves a processing rate of 21 elastograms per second at an image size of 960 × 400 pixels, enabling high-rate visualization during acquisition. The system is demonstrated on both tissue-simulating phantoms and fresh ex vivo mouse muscle. To the best of our knowledge, this is the first implementation of near video-rate OCE and the fastest reported OCE processing rate, enabling, for the first time, a system capable of computing and displaying OCE elastograms interactively during acquisition. This advance provides new opportunities for medical imaging of soft tissue stiffness using optical methods.

Original language	English
Pages (from-to)	3481-3485
Journal	Journal of Lightwave Technology
Volume	33
Issue number	16
DOIs	https://doi.org/10.1109/JLT.2015.2413402
Publication status	Published - 15 Aug 2015

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abstract = "{\textcopyright} 2015 IEEE. We present a graphics processing unit (GPU)-accelerated optical coherence elastography (OCE) system capable of generating strain images (elastograms) of soft tissue at near video-rates. The system implements phase-sensitive compression OCE using a pipeline of GPU kernel functions to enable a highly parallel implementation of OCE processing using the OpenCL framework. Developed on a commercial-grade GPU and desktop computer, the system achieves a processing rate of 21 elastograms per second at an image size of 960 × 400 pixels, enabling high-rate visualization during acquisition. The system is demonstrated on both tissue-simulating phantoms and fresh ex vivo mouse muscle. To the best of our knowledge, this is the first implementation of near video-rate OCE and the fastest reported OCE processing rate, enabling, for the first time, a system capable of computing and displaying OCE elastograms interactively during acquisition. This advance provides new opportunities for medical imaging of soft tissue stiffness using optical methods.",

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Near Video-Rate Optical Coherence Elastography by Acceleration With a Graphics Processing Unit

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