Narcolepsy: Comorbidities, complexities and future directions

Sajni Gudka; Emma Haynes; Joanne Scotney; Sutapa Mukherjee; Simon Frenkel; Sheila Sivam; John Swieca; Ksenia Chamula; David Cunnington; Bandana Saini

doi:10.1016/j.smrv.2022.101669

Narcolepsy: Comorbidities, complexities and future directions

Sajni Gudka, Emma Haynes, Joanne Scotney, Sutapa Mukherjee, Simon Frenkel, Sheila Sivam, John Swieca, Ksenia Chamula, David Cunnington, Bandana Saini

Research output: Contribution to journal › Review article › peer-review

10 Citations (Scopus)

Abstract

Patients with narcolepsy live with a lifelong sleep-wake disorder, impairing their quality of life, productivity, educational and employment outcomes. Clinicians are becoming aware that a significant aspect of the burden of this disease relates to frequent comorbid conditions, including aspects of the patient's emotional, metabolic, sleep and immune health. This review explores the literature describing the comorbidities seen in patients with narcolepsy, to enhance understanding of these often complex presentations. It hopes to encourage a multidisciplinary approach, to collaborate with patients and a broad clinical team, and to maximise clinical and quality of life outcomes, for those living with narcolepsy.

Original language	English
Article number	101669
Journal	Sleep Medicine Reviews
Volume	65
DOIs	https://doi.org/10.1016/j.smrv.2022.101669
Publication status	Published - Oct 2022

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10.1016/j.smrv.2022.101669

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title = "Narcolepsy: Comorbidities, complexities and future directions",

abstract = "Patients with narcolepsy live with a lifelong sleep-wake disorder, impairing their quality of life, productivity, educational and employment outcomes. Clinicians are becoming aware that a significant aspect of the burden of this disease relates to frequent comorbid conditions, including aspects of the patient's emotional, metabolic, sleep and immune health. This review explores the literature describing the comorbidities seen in patients with narcolepsy, to enhance understanding of these often complex presentations. It hopes to encourage a multidisciplinary approach, to collaborate with patients and a broad clinical team, and to maximise clinical and quality of life outcomes, for those living with narcolepsy.",

keywords = "Cataplexy, Chronic disease, Comorbidity, Hypersomnia, Literature review, Multidisciplinary, Narcolepsy, Sleep disorders",

author = "Sajni Gudka and Emma Haynes and Joanne Scotney and Sutapa Mukherjee and Simon Frenkel and Sheila Sivam and John Swieca and Ksenia Chamula and David Cunnington and Bandana Saini",

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T2 - Comorbidities, complexities and future directions

AU - Gudka, Sajni

AU - Haynes, Emma

AU - Scotney, Joanne

AU - Mukherjee, Sutapa

AU - Frenkel, Simon

AU - Sivam, Sheila

AU - Swieca, John

AU - Chamula, Ksenia

AU - Cunnington, David

AU - Saini, Bandana

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AB - Patients with narcolepsy live with a lifelong sleep-wake disorder, impairing their quality of life, productivity, educational and employment outcomes. Clinicians are becoming aware that a significant aspect of the burden of this disease relates to frequent comorbid conditions, including aspects of the patient's emotional, metabolic, sleep and immune health. This review explores the literature describing the comorbidities seen in patients with narcolepsy, to enhance understanding of these often complex presentations. It hopes to encourage a multidisciplinary approach, to collaborate with patients and a broad clinical team, and to maximise clinical and quality of life outcomes, for those living with narcolepsy.

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KW - Comorbidity

KW - Hypersomnia

KW - Literature review

KW - Multidisciplinary

KW - Narcolepsy

KW - Sleep disorders

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VL - 65

JO - Sleep Medicine Reviews

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Narcolepsy: Comorbidities, complexities and future directions

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