Murray valley encephalitis mimicking herpes simplex encephalitis

S.H. Wong; David Smith; M.J. Fallon; A.G. Kermode

doi:10.1016/j.jocn.2004.10.010

Murray valley encephalitis mimicking herpes simplex encephalitis

S.H. Wong, David Smith, M.J. Fallon, A.G. Kermode

Research output: Contribution to journal › Review article

21 Citations (Scopus)

Abstract

We describe a patient with serologically proven Murray Valley encephalitis (MVE), whose presentation was clinically and radiologically characteristic of Herpes simplex encephalitis (HSE). The reports of MRI abnormalities in MVE, and the closely related Japanese Encephalitis and West Nile virusii are mostly of bilateral thalamic or grey matter involvement. The MRI scan findings in this case instead showed the typical temporal lobe changes of HSE. Our case report highlights that MVE can mimic HSE, both clinically and radiologically. Therefore it is important to collect an accurate and detailed travel history from patients where there is a risk of exposure to MVE virus. If suspected, antibody testing of serum and CSF, and CSF for MVE-RNA if available, should be undertaken. This case also highlights the potential under-diagnosis of Murray Valley encephalitis. (c) 2005 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	822-824
Journal	Journal of Clinical Neuroscience
Volume	12
Issue number	7
DOIs	https://doi.org/10.1016/j.jocn.2004.10.010
Publication status	Published - 2005

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10.1016/j.jocn.2004.10.010

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title = "Murray valley encephalitis mimicking herpes simplex encephalitis",

abstract = "We describe a patient with serologically proven Murray Valley encephalitis (MVE), whose presentation was clinically and radiologically characteristic of Herpes simplex encephalitis (HSE). The reports of MRI abnormalities in MVE, and the closely related Japanese Encephalitis and West Nile virusii are mostly of bilateral thalamic or grey matter involvement. The MRI scan findings in this case instead showed the typical temporal lobe changes of HSE. Our case report highlights that MVE can mimic HSE, both clinically and radiologically. Therefore it is important to collect an accurate and detailed travel history from patients where there is a risk of exposure to MVE virus. If suspected, antibody testing of serum and CSF, and CSF for MVE-RNA if available, should be undertaken. This case also highlights the potential under-diagnosis of Murray Valley encephalitis. (c) 2005 Elsevier Ltd. All rights reserved.",

author = "S.H. Wong and David Smith and M.J. Fallon and A.G. Kermode",

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T1 - Murray valley encephalitis mimicking herpes simplex encephalitis

AU - Wong, S.H.

AU - Smith, David

AU - Fallon, M.J.

AU - Kermode, A.G.

PY - 2005

Y1 - 2005

N2 - We describe a patient with serologically proven Murray Valley encephalitis (MVE), whose presentation was clinically and radiologically characteristic of Herpes simplex encephalitis (HSE). The reports of MRI abnormalities in MVE, and the closely related Japanese Encephalitis and West Nile virusii are mostly of bilateral thalamic or grey matter involvement. The MRI scan findings in this case instead showed the typical temporal lobe changes of HSE. Our case report highlights that MVE can mimic HSE, both clinically and radiologically. Therefore it is important to collect an accurate and detailed travel history from patients where there is a risk of exposure to MVE virus. If suspected, antibody testing of serum and CSF, and CSF for MVE-RNA if available, should be undertaken. This case also highlights the potential under-diagnosis of Murray Valley encephalitis. (c) 2005 Elsevier Ltd. All rights reserved.

AB - We describe a patient with serologically proven Murray Valley encephalitis (MVE), whose presentation was clinically and radiologically characteristic of Herpes simplex encephalitis (HSE). The reports of MRI abnormalities in MVE, and the closely related Japanese Encephalitis and West Nile virusii are mostly of bilateral thalamic or grey matter involvement. The MRI scan findings in this case instead showed the typical temporal lobe changes of HSE. Our case report highlights that MVE can mimic HSE, both clinically and radiologically. Therefore it is important to collect an accurate and detailed travel history from patients where there is a risk of exposure to MVE virus. If suspected, antibody testing of serum and CSF, and CSF for MVE-RNA if available, should be undertaken. This case also highlights the potential under-diagnosis of Murray Valley encephalitis. (c) 2005 Elsevier Ltd. All rights reserved.

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DO - 10.1016/j.jocn.2004.10.010

M3 - Review article

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VL - 12

SP - 822

EP - 824

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

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ER -

Murray valley encephalitis mimicking herpes simplex encephalitis

Abstract

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