Multivariate risk estimation for coronary heart disease: the Busselton Health Study

Matthew Knuiman, H.T.V. Vu, Helen Bartholomew

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Coronary heart disease (CHD) is a multifactorial disease and CHD risk should be estimated by assessing all cardiovascular risk factors simultaneously. Simply adding up the number of factors with 'at risk' values fails to identify high-risk subjects with multiple risk factors at moderately elevated values. A more efficient approach is to use a quantitative multivariate risk score. A number of overseas studies have produced CHD risk scoring systems for men. There are few risk scores developed for women and no CHD risk scores have been developed from Australian data. This study used data on CHD risk factors and morbidity/mortality follow-up for the 1978 Busselton Health Survey participants to provide age-specific estimates of absolute risk of CHD hospitalisation or death, and to develop multivariate CHD risk scoring systems for men and women. The scores are based on age, blood pressure, anti-hypertensive medication, total and HDL cholesterol, smoking, diabetes, left ventricular hypertrophy and previous history of CHD. The generalisability and applicability of these risk estimation systems to Australian populations in the late 1990s is discussed.
Original languageEnglish
Pages (from-to)747-753
JournalAustralian and New Zealand Journal of Public Health
Issue number7
Publication statusPublished - 1998


Dive into the research topics of 'Multivariate risk estimation for coronary heart disease: the Busselton Health Study'. Together they form a unique fingerprint.

Cite this