Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases

Paul C. Guest; Mitra Abbasifard; Tannaz Jamialahmadi; Muhammed Majeed; Prashant Kesharwani; Amirhossein Sahebkar

doi:10.1007/978-1-0716-2395-4_18

Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases

Paul C. Guest, Mitra Abbasifard, Tannaz Jamialahmadi, Muhammed Majeed, Prashant Kesharwani, Amirhossein Sahebkar

UWA Medical School

Research output: Chapter in Book/Conference paper › Chapter › peer-review

5 Citations (Scopus)

Abstract

Severe cases of SARS-CoV-2 and other pathogenic virus infections are often associated with the uncontrolled release of proinflammatory cytokines, known as a “cytokine storm.” We present a protocol for multiplex analysis of three cytokines, tumor necrosis factor-alpha (TNF-a), interleukin 6 (IL-6), and IL-10, which are typically elevated in cytokine storm events and may be used as a predictive biomarker profile of disease severity or disease course.

Original language	English
Title of host publication	Methods in Molecular Biology
Editors	Paul Guest
Publisher	Humana Press Inc.
Pages	245-256
Number of pages	12
DOIs	https://doi.org/10.1007/978-1-0716-2395-4_18
Publication status	Published - 2022

Publication series

Name	Methods in Molecular Biology
Volume	2511
ISSN (Print)	1064-3745
ISSN (Electronic)	1940-6029

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10.1007/978-1-0716-2395-4_18

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Guest, P. C., Abbasifard, M., Jamialahmadi, T., Majeed, M., Kesharwani, P., & Sahebkar, A. (2022). Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases. In P. Guest (Ed.), Methods in Molecular Biology (pp. 245-256). (Methods in Molecular Biology; Vol. 2511). Humana Press Inc.. https://doi.org/10.1007/978-1-0716-2395-4_18

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abstract = "Severe cases of SARS-CoV-2 and other pathogenic virus infections are often associated with the uncontrolled release of proinflammatory cytokines, known as a “cytokine storm.” We present a protocol for multiplex analysis of three cytokines, tumor necrosis factor-alpha (TNF-a), interleukin 6 (IL-6), and IL-10, which are typically elevated in cytokine storm events and may be used as a predictive biomarker profile of disease severity or disease course.",

keywords = "COVID-19, Cytokine storm, IL-10, IL-6, Multiplex immunoassay, SARS-CoV-2, TNF-α",

author = "Guest, {Paul C.} and Mitra Abbasifard and Tannaz Jamialahmadi and Muhammed Majeed and Prashant Kesharwani and Amirhossein Sahebkar",

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doi = "10.1007/978-1-0716-2395-4_18",

language = "English",

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Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases. / Guest, Paul C.; Abbasifard, Mitra; Jamialahmadi, Tannaz et al.
Methods in Molecular Biology. ed. / Paul Guest. Humana Press Inc., 2022. p. 245-256 (Methods in Molecular Biology; Vol. 2511).

Research output: Chapter in Book/Conference paper › Chapter › peer-review

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AU - Kesharwani, Prashant

AU - Sahebkar, Amirhossein

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Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases

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