Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases

Paul C. Guest, Mitra Abbasifard, Tannaz Jamialahmadi, Muhammed Majeed, Prashant Kesharwani, Amirhossein Sahebkar

Research output: Chapter in Book/Conference paperChapterpeer-review

Abstract

Severe cases of SARS-CoV-2 and other pathogenic virus infections are often associated with the uncontrolled release of proinflammatory cytokines, known as a “cytokine storm.” We present a protocol for multiplex analysis of three cytokines, tumor necrosis factor-alpha (TNF-a), interleukin 6 (IL-6), and IL-10, which are typically elevated in cytokine storm events and may be used as a predictive biomarker profile of disease severity or disease course.
Original languageEnglish
Title of host publicationMethods in Molecular Biology
EditorsPaul Guest
PublisherHumana Press
Pages245-256
Number of pages12
DOIs
Publication statusPublished - 2022

Publication series

NameMethods in Molecular Biology
Volume2511
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Fingerprint

Dive into the research topics of 'Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases'. Together they form a unique fingerprint.

Cite this