Multi-model approach shows novel and diverse effects of low-intensity repetitive transcranial magnetic stimulation on brain cells and behaviour

Research output: ThesisDoctoral Thesis

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Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique used to treat neurological disorders and modulate cognition. Although rTMS can induce various benefits, its mechanisms are not well understood. Recent research with animal models has used low intensity (LI-) rTMS to explore mechanisms, with evidence of cellular changes and limited behavioural effects. Therefore this thesis aims to expand LI-rTMS research to a wider scope, from subcellular to network levels. This thesis investigates LI-rTMS-induced changes in mitochondria, whole-brain neuronal activity and functional connectivity, and investigates behavioural effects, both in animal models and, for the first time, in humans.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Rodger, Jennifer, Supervisor
  • Visser, Troy, Supervisor
  • Harvey, Alan, Supervisor
Thesis sponsors
Award date11 Jun 2023
DOIs
Publication statusUnpublished - 2023

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