Mucocoele-like lesions: is surgical excision still necessary?

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Aim To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. Materials and methods A retrospective review of the breast screening database from 1999–2014 was performed. Results MLL were identified on core biopsy in 113 women (0.6% of those recalled for a core biopsy). The majority (n=100, 88%) had a localised cluster of calcification prompting screening recall. Eighty-seven percent (n=99) underwent an excision biopsy; there was a 5% upgrade rate to malignancy (all low/intermediate ductal carcinoma in situ [DCIS]) and 15 women (15%) were found to have an additional “B3” lesion. Fourteen women did not undergo excision biopsy; none of these women had a subsequent cancer at an average of 5-years follow-up. Within the follow-up period, five additional cancers were identified, one of these was in the ipsilateral breast and location, albeit 9-years later. Conclusion This is the largest study of MLL in the literature to date. The present findings show a 5% upgrade rate to DCIS. As long as the current management of low-risk DCIS remains surgical excision, the present results support continued excision of MLLs, either surgically or by vacuum-assisted biopsy.

Original languageEnglish
Pages (from-to)992.e1-992.e6
JournalClinical Radiology
Volume72
Issue number11
DOIs
Publication statusPublished - 1 Nov 2017

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Mucocele
Biopsy
Carcinoma, Intraductal, Noninfiltrating
Breast
Neoplasms
Risk Management
Vacuum
Databases
Population

Cite this

@article{40ecb17a03884892b295e7d12d3859e7,
title = "Mucocoele-like lesions: is surgical excision still necessary?",
abstract = "Aim To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. Materials and methods A retrospective review of the breast screening database from 1999–2014 was performed. Results MLL were identified on core biopsy in 113 women (0.6{\%} of those recalled for a core biopsy). The majority (n=100, 88{\%}) had a localised cluster of calcification prompting screening recall. Eighty-seven percent (n=99) underwent an excision biopsy; there was a 5{\%} upgrade rate to malignancy (all low/intermediate ductal carcinoma in situ [DCIS]) and 15 women (15{\%}) were found to have an additional “B3” lesion. Fourteen women did not undergo excision biopsy; none of these women had a subsequent cancer at an average of 5-years follow-up. Within the follow-up period, five additional cancers were identified, one of these was in the ipsilateral breast and location, albeit 9-years later. Conclusion This is the largest study of MLL in the literature to date. The present findings show a 5{\%} upgrade rate to DCIS. As long as the current management of low-risk DCIS remains surgical excision, the present results support continued excision of MLLs, either surgically or by vacuum-assisted biopsy.",
author = "I. Dash and B. Dessauvagie and M. Hardie and C. Saunders and E. Wylie",
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Mucocoele-like lesions : is surgical excision still necessary? / Dash, I.; Dessauvagie, B.; Hardie, M.; Saunders, C.; Wylie, E.

In: Clinical Radiology, Vol. 72, No. 11, 01.11.2017, p. 992.e1-992.e6.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Mucocoele-like lesions

T2 - is surgical excision still necessary?

AU - Dash, I.

AU - Dessauvagie, B.

AU - Hardie, M.

AU - Saunders, C.

AU - Wylie, E.

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Aim To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. Materials and methods A retrospective review of the breast screening database from 1999–2014 was performed. Results MLL were identified on core biopsy in 113 women (0.6% of those recalled for a core biopsy). The majority (n=100, 88%) had a localised cluster of calcification prompting screening recall. Eighty-seven percent (n=99) underwent an excision biopsy; there was a 5% upgrade rate to malignancy (all low/intermediate ductal carcinoma in situ [DCIS]) and 15 women (15%) were found to have an additional “B3” lesion. Fourteen women did not undergo excision biopsy; none of these women had a subsequent cancer at an average of 5-years follow-up. Within the follow-up period, five additional cancers were identified, one of these was in the ipsilateral breast and location, albeit 9-years later. Conclusion This is the largest study of MLL in the literature to date. The present findings show a 5% upgrade rate to DCIS. As long as the current management of low-risk DCIS remains surgical excision, the present results support continued excision of MLLs, either surgically or by vacuum-assisted biopsy.

AB - Aim To assess the rate of upgrade in our screening population to determine whether open excision biopsy of mucocoele-like lesions (MLL) is still required. Materials and methods A retrospective review of the breast screening database from 1999–2014 was performed. Results MLL were identified on core biopsy in 113 women (0.6% of those recalled for a core biopsy). The majority (n=100, 88%) had a localised cluster of calcification prompting screening recall. Eighty-seven percent (n=99) underwent an excision biopsy; there was a 5% upgrade rate to malignancy (all low/intermediate ductal carcinoma in situ [DCIS]) and 15 women (15%) were found to have an additional “B3” lesion. Fourteen women did not undergo excision biopsy; none of these women had a subsequent cancer at an average of 5-years follow-up. Within the follow-up period, five additional cancers were identified, one of these was in the ipsilateral breast and location, albeit 9-years later. Conclusion This is the largest study of MLL in the literature to date. The present findings show a 5% upgrade rate to DCIS. As long as the current management of low-risk DCIS remains surgical excision, the present results support continued excision of MLLs, either surgically or by vacuum-assisted biopsy.

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