MRI Measurements of Iron Load in Transfusion-Dependent Patients: Implementation, Challenges, and Pitfalls

C.T. Quinn, Tim St Pierre

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    © 2016 Wiley Periodicals, Inc. Magnetic resonance imaging (MRI) has played a key role in studies of iron overload in transfusion-dependent patients, providing insights into the relations among liver and cardiac iron loading, iron chelator dose, and morbidity. Currently, there is rapid uptake of these methods into routine clinical practice as part of the management strategy for iron overload in regularly transfused patients. Given the manifold methods of data acquisition and analysis, there are several potential pitfalls that may result in inappropriate decision making. Herein, we review the challenges of establishing suitable MRI techniques for tissue iron measurement in regularly transfused patients.
    Original languageEnglish
    Pages (from-to)773-780
    JournalPediatric Blood and Cancer
    Volume63
    Issue number5
    DOIs
    Publication statusPublished - 2016

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