More trials for the unhappy hypothyroid patient on thyroxine: a clinician's perspective

Research output: Contribution to journalShort surveypeer-review

Abstract

Further clinical trials are proposed for the 5–15% of hypothyroid patients who are dissatisfied with thyroxine (T4) monotherapy. Those responding to combination therapy [T4 plus triiodothyronine (T3)] will show suggestive biochemistry and abnormal reflexes. Those with Hashimoto's disease and very high anti-thyroid peroxidase (anti-TPO) thyroid antibody levels may benefit from total thyroidectomy. The remainder have negative clinical and laboratory findings and require supportive management.

Original languageEnglish
Pages (from-to)536-538
Number of pages3
JournalTrends in Endocrinology and Metabolism
Volume33
Issue number8
Early online date2022
DOIs
Publication statusPublished - Aug 2022

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