Molecular pathogenesis of iron overload

Debbie Trinder; C. Fox; G. Vautier; John Olynyk

doi:10.1136/gut.51.2.290

Molecular pathogenesis of iron overload

Debbie Trinder, C. Fox, G. Vautier, John Olynyk

Research output: Contribution to journal › Review article › peer-review

69 Citations (Scopus)

Abstract

Our current understanding of iron absorption under normal conditions is presented, together with an overview of the clinical disorders of iron overload and the molecular processes that contribute to increased iron deposition in iron overload. Recently, a number of new genes involved in iron metabolism have been identified which is allowing the molecular mechanisms of iron absorption to be elucidated.

Original language	English
Pages (from-to)	290-295
Journal	Gut
Volume	51
DOIs	https://doi.org/10.1136/gut.51.2.290
Publication status	Published - 2002

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10.1136/gut.51.2.290

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title = "Molecular pathogenesis of iron overload",

abstract = "Our current understanding of iron absorption under normal conditions is presented, together with an overview of the clinical disorders of iron overload and the molecular processes that contribute to increased iron deposition in iron overload. Recently, a number of new genes involved in iron metabolism have been identified which is allowing the molecular mechanisms of iron absorption to be elucidated.",

author = "Debbie Trinder and C. Fox and G. Vautier and John Olynyk",

year = "2002",

doi = "10.1136/gut.51.2.290",

language = "English",

volume = "51",

pages = "290--295",

journal = "Gut",

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T1 - Molecular pathogenesis of iron overload

AU - Trinder, Debbie

AU - Fox, C.

AU - Vautier, G.

AU - Olynyk, John

PY - 2002

Y1 - 2002

N2 - Our current understanding of iron absorption under normal conditions is presented, together with an overview of the clinical disorders of iron overload and the molecular processes that contribute to increased iron deposition in iron overload. Recently, a number of new genes involved in iron metabolism have been identified which is allowing the molecular mechanisms of iron absorption to be elucidated.

AB - Our current understanding of iron absorption under normal conditions is presented, together with an overview of the clinical disorders of iron overload and the molecular processes that contribute to increased iron deposition in iron overload. Recently, a number of new genes involved in iron metabolism have been identified which is allowing the molecular mechanisms of iron absorption to be elucidated.

U2 - 10.1136/gut.51.2.290

DO - 10.1136/gut.51.2.290

M3 - Review article

SN - 0017-5749

VL - 51

SP - 290

EP - 295

JO - Gut

JF - Gut

ER -

Molecular pathogenesis of iron overload

Abstract

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