Molecular genetic analysis of haematological malignancies: I. Acute leukaemias and myeloproliferative disorders

Anthony J. Bench; W. N. Erber; M. A. Scott

doi:10.1111/j.1365-2257.2005.00701.x

Molecular genetic analysis of haematological malignancies: I. Acute leukaemias and myeloproliferative disorders

Anthony J. Bench, W. N. Erber, M. A. Scott

Research output: Contribution to journal › Review article › peer-review

23 Citations (Scopus)

Abstract

Molecular genetic techniques are now routinely applied to haematological malignancies within a clinical laboratory setting. The detection of genetic rearrangements not only assists with diagnosis and treatment decisions, but also adds important prognostic information. In addition, genetic rearrangements associated with leukaemia can be used as molecular markers allowing the detection of low levels of residual disease. This review will concentrate on the application of molecular genetic techniques to the acute leukaemias and myeloproliferative disorders.

Original language	English
Pages (from-to)	148-171
Number of pages	24
Journal	Clinical and Laboratory Haematology
Volume	27
Issue number	3
DOIs	https://doi.org/10.1111/j.1365-2257.2005.00701.x
Publication status	Published - 1 Jun 2005
Externally published	Yes

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10.1111/j.1365-2257.2005.00701.x

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KW - Chronic myeloproliferative disorders

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KW - Polymerase chain reaction

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Molecular genetic analysis of haematological malignancies: I. Acute leukaemias and myeloproliferative disorders

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