Mitophagy: A Mechanism for Plant Growth and Survival

Martyna Broda, A. Harvey Millar, Olivier Van Aken

Research output: Contribution to journalReview article

17 Citations (Scopus)
488 Downloads (Pure)

Abstract

Mitophagy is a conserved cellular process that is important for autophagic removal of damaged mitochondria to maintain a healthy mitochondrial population. Mitophagy also appears to occur in plants and has roles in development, stress response, senescence, and programmed cell death. However, many of the genes that control mitophagy in yeast and animal cells are absent from plants, and no plant proteins marking defunct mitochondria for autophagic degradation are yet known. New insights implicate general autophagy-related proteins in mitophagy, affecting the senescence of plant tissues. Mitophagy control and its importance for energy metabolism, survival, signaling, and cell death in plants are discussed. Furthermore, we suggest mitochondrial membrane proteins containing ATG8-interacting motifs, which might serve as mitophagy receptor proteins in plant mitochondria.

Original languageEnglish
Pages (from-to)434-450
Number of pages17
JournalTrends in Plant Science
Volume23
Issue number5
DOIs
Publication statusPublished - 1 May 2018

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