Minimum Information about a Biosynthetic Gene cluster

M.H. Medema, R. Kottmann, P. Yilmaz, M. Cummings, J.B. Biggins, K. Blin, I. De Bruijn, Heng Chooi, J. Claesen, R.C. Coates, P. Cruz-Morales, S. Duddela, S. Düsterhus, D.J. Edwards, D.P. Fewer, N. Garg, C. Geiger, J.P. Gomez-Escribano, A. Greule, M. HadjithomasA.S. Haines, E.J.N. Helfrich, M.L. Hillwig, K. Ishida, A.C. Jones, C.S. Jones, K. Jungmann, C. Kegler, H.U. Kim, P. Kötter, D. Krug, J. Masschelein, A.V. Melnik, S.M. Mantovani, E.A. Monroe, M. Moore, N. Moss, H.W. Nützmann, G. Pan, A. Pati, D. Petras, F.J. Reen, F. Rosconi, Z. Rui, Z. Tian, N.J. Tobias, Y. Tsunematsu, P. Wiemann, E. Wyckoff, X. Yan, G. Yim, F. Yu, Y. Xie, B. Aigle, A.K. Apel, C.J. Balibar, E.P. Balskus, F. Barona-Gómez, A. Bechthold, H.B. Bode, R. Borriss, S.F. Brady, A.A. Brakhage, P. Caffrey, Y.Q. Cheng, J. Clardy, R.J. Cox, R. De Mot, S. Donadio, M.S. Donia, W.A. Van Der Donk, P.C. Dorrestein, S. Doyle, A.J.M. Driessen, M. Ehling-Schulz, K.D. Entian, M.A. Fischbach, L. Gerwick, W.H. Gerwick, H. Gross

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623 Citations (Scopus)

Abstract

© 2015 Nature America, Inc. All rights reserved. A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.
Original languageEnglish
Pages (from-to)625-631
JournalNature Chemical Biology
Volume11
Issue number9
DOIs
Publication statusPublished - 2015

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