Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display

Jiawen Li, T. Ma, J. Jing, J. Zhang, P.M. Patel, K. Kirk Shung, Q. Zhou, Z. Chen

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    31 Citations (Scopus)

    Abstract

    We have developed a novel miniature integrated optical coherence tomography (OCT)-intravascular ultrasound (IVUS) probe, with a 1.5-mm-long rigid part and 0.9-mm outer diameter, for real-time intracoronary imaging of atherosclerotic plaques and guiding of interventional procedures. By placing the OCT ball lens and IVUS transducer back-to-back at the same axial position, this probe can provide automatically coregistered, coaxial OCT-IVUS imaging. To demonstrate its real-time capability, threedimensional OCT-IVUS imaging of a pig's coronary artery displaying in polar coordinates, as well as images of three major types of atherosclerotic plaques in human cadaver coronary segments, were obtained using this probe and our upgraded system. Histology validation is also presented. © 2013 Society of Photo-Optical Instrumentation Engineers.
    Original languageEnglish
    Pages (from-to)1-4
    JournalJournal of Biomedical Optics
    Volume18
    Issue number10
    DOIs
    Publication statusPublished - 2013

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