Millimeter Waves Alter the Genomic Architecture and Transcriptome of Primary Human Fibroblasts

Research output: Chapter in Book/Conference paperConference paperpeer-review

1 Citation (Scopus)

Abstract

The current understanding of the biological effects of millimeter waves (MMWs) remains incomplete, and the interaction mechanisms causing these effects are largely unknown. We found that exposure of primary human fibroblasts to MMWs results in modified DNA secondary structure formation, altering the transcriptome and enriching many biological pathways without inducing DNA damage. This establishes the potential for therapeutic application of MMWs to induce targeted modifications to genomic architecture for the purpose of controlling gene expression and specific pathways.
Original languageEnglish
Title of host publicationIRMMW-THz 2022 - 47th International Conference on Infrared, Millimeter and Terahertz Waves
PublisherIEEE, Institute of Electrical and Electronics Engineers
Number of pages2
ISBN (Electronic)9781728194271
DOIs
Publication statusPublished - 2022
Event47th International Conference on Infrared, Millimeter and Terahertz Waves, IRMMW-THz 2022 - Delft, Netherlands
Duration: 28 Aug 20222 Sept 2022

Publication series

NameInternational Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
Volume2022-August
ISSN (Print)2162-2027
ISSN (Electronic)2162-2035

Conference

Conference47th International Conference on Infrared, Millimeter and Terahertz Waves, IRMMW-THz 2022
Country/TerritoryNetherlands
CityDelft
Period28/08/222/09/22

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