Microbial metabolites: the next frontier in human milk

Lisa F. Stinson; Donna T. Geddes

doi:10.1016/j.tim.2022.02.007

Microbial metabolites: the next frontier in human milk

School of Molecular Sciences

Research output: Contribution to journal › Short survey › peer-review

32 Citations (Scopus)

Abstract

Microbial metabolites mediate the impact of the microbiome on host physiology. Here, we highlight metabolites of interest for early-life programming and synthesise early evidence that maternally derived microbial metabolites are transmitted to the infant via human milk. We advocate for the use of targeted and untargeted metabolomics to compliment current milk microbiome work.

Original language	English
Pages (from-to)	408-410
Number of pages	3
Journal	Trends in Microbiology
Volume	30
Issue number	5
DOIs	https://doi.org/10.1016/j.tim.2022.02.007
Publication status	Published - May 2022

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10.1016/j.tim.2022.02.007

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title = "Microbial metabolites: the next frontier in human milk",

abstract = "Microbial metabolites mediate the impact of the microbiome on host physiology. Here, we highlight metabolites of interest for early-life programming and synthesise early evidence that maternally derived microbial metabolites are transmitted to the infant via human milk. We advocate for the use of targeted and untargeted metabolomics to compliment current milk microbiome work.",

keywords = "breastfeeding, human milk, microbial metabolites, short-chain fatty acids",

author = "Stinson, \{Lisa F.\} and Geddes, \{Donna T.\}",

note = "Funding Information: L.F.S. and D.T.G. receive funding from Medela AG, Switzerland. This funding body had no input into the writing of this manuscript or decision to publish. Publisher Copyright: {\textcopyright} 2022 Elsevier Ltd",

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AU - Geddes, Donna T.

N1 - Funding Information: L.F.S. and D.T.G. receive funding from Medela AG, Switzerland. This funding body had no input into the writing of this manuscript or decision to publish. Publisher Copyright: © 2022 Elsevier Ltd

PY - 2022/5

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N2 - Microbial metabolites mediate the impact of the microbiome on host physiology. Here, we highlight metabolites of interest for early-life programming and synthesise early evidence that maternally derived microbial metabolites are transmitted to the infant via human milk. We advocate for the use of targeted and untargeted metabolomics to compliment current milk microbiome work.

AB - Microbial metabolites mediate the impact of the microbiome on host physiology. Here, we highlight metabolites of interest for early-life programming and synthesise early evidence that maternally derived microbial metabolites are transmitted to the infant via human milk. We advocate for the use of targeted and untargeted metabolomics to compliment current milk microbiome work.

KW - breastfeeding

KW - human milk

KW - microbial metabolites

KW - short-chain fatty acids

UR - https://www.scopus.com/pages/publications/85126098899

U2 - 10.1016/j.tim.2022.02.007

DO - 10.1016/j.tim.2022.02.007

M3 - Short survey

C2 - 35282976

AN - SCOPUS:85126098899

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VL - 30

SP - 408

EP - 410

JO - Trends in Microbiology

JF - Trends in Microbiology

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ER -

Microbial metabolites: the next frontier in human milk

Abstract

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