Microarray fabrication; the importance of library curation

John W. Barlow, Lisa M. Morris, Melanie O'Keefe, Cathy Jensen, Anthea Downs, Wendy N. Erber

Research output: Contribution to journalArticle

Abstract

Microarray technology, via the deposition of cDNA or oligonucleotide libraries on to microscope slides for hybridisation by a labelled reverse transcribed RNA, is becoming an increasingly popular method to analyse patterns of gene expression. The production of high quality, inexpensive cDNA microarrays is critically dependent on the quality of the cDNA libraries. Full curation of the libraries is essential to allow correct interpretation of whole library arrays and efficient fabrication of complete custom arrays.

Original languageEnglish
Pages (from-to)46-48
Number of pages3
JournalToday's Life Science
Volume14
Issue number5
Publication statusPublished - 1 Sep 2002
Externally publishedYes

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