Methadone-Induced Toxic Leukoencephalopathy: MR Imaging and MR Proton Spectroscopy Findings

R. A. Salgado, P. G. Jorens, I. Baar, P. Cras, G. Hans, P. M. Parizel

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We report the clinical, MR imaging, and proton MR spectroscopy findings in a middle-aged woman with proved methadone-induced toxic leukoencephalopathy. The imaging characteristics of this unusual condition have beer reported only rarely in the medical literature. We show that the imaging findings in methadone-induced toxic leukoencephalopathy are similar, though not identical, to previously reported cases of neurologic deterioration due to heroin inhalation.

Original languageEnglish
Pages (from-to)565-566
Number of pages2
JournalAmerican Journal of Neuroradiology
Issue number3
Publication statusPublished - Mar 2010
Externally publishedYes

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