Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase

M.S. Macauley; J. Chan; W.F. Zandberg; Y. He; G.E. Whitworth; Keith Stubbs; S.A. Yuzwa; A.J. Bennet; A. Varki; G.J. Davies; D.J. Vocadlo

doi:10.1074/jbc.M112.363721

Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase

M.S. Macauley, J. Chan, W.F. Zandberg, Y. He, G.E. Whitworth, Keith Stubbs, S.A. Yuzwa, A.J. Bennet, A. Varki, G.J. Davies, D.J. Vocadlo

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Original language	English
Pages (from-to)	28882-28897
Journal	Journal of Biological Chemistry
Volume	287
Issue number	34
DOIs	https://doi.org/10.1074/jbc.M112.363721
Publication status	Published - 2012

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10.1074/jbc.M112.363721

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Macauley, M. S., Chan, J., Zandberg, W. F., He, Y., Whitworth, G. E., Stubbs, K., Yuzwa, S. A., Bennet, A. J., Varki, A., Davies, G. J., & Vocadlo, D. J. (2012). Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase. Journal of Biological Chemistry, 287(34), 28882-28897. https://doi.org/10.1074/jbc.M112.363721

Macauley, M.S. ; Chan, J. ; Zandberg, W.F. et al. / Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase. In: Journal of Biological Chemistry. 2012 ; Vol. 287, No. 34. pp. 28882-28897.

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title = "Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase",

author = "M.S. Macauley and J. Chan and W.F. Zandberg and Y. He and G.E. Whitworth and Keith Stubbs and S.A. Yuzwa and A.J. Bennet and A. Varki and G.J. Davies and D.J. Vocadlo",

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Macauley, MS, Chan, J, Zandberg, WF, He, Y, Whitworth, GE, Stubbs, K, Yuzwa, SA, Bennet, AJ, Varki, A, Davies, GJ & Vocadlo, DJ 2012, 'Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase', Journal of Biological Chemistry, vol. 287, no. 34, pp. 28882-28897. https://doi.org/10.1074/jbc.M112.363721

Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase. / Macauley, M.S.; Chan, J.; Zandberg, W.F. et al.

In: Journal of Biological Chemistry, Vol. 287, No. 34, 2012, p. 28882-28897.

Research output: Contribution to journal › Article › peer-review

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T1 - Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase

AU - Macauley, M.S.

AU - Chan, J.

AU - Zandberg, W.F.

AU - He, Y.

AU - Whitworth, G.E.

AU - Stubbs, Keith

AU - Yuzwa, S.A.

AU - Bennet, A.J.

AU - Varki, A.

AU - Davies, G.J.

AU - Vocadlo, D.J.

PY - 2012

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DO - 10.1074/jbc.M112.363721

M3 - Article

C2 - 22692202

VL - 287

SP - 28882

EP - 28897

JO - The Journal of Biological Chemistry

JF - The Journal of Biological Chemistry

SN - 0021-9258

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Macauley MS, Chan J, Zandberg WF, He Y, Whitworth GE, Stubbs K et al. Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of β-O-linked& beta;-N-acetylglucosaminidase. Journal of Biological Chemistry. 2012;287(34):28882-28897. https://doi.org/10.1074/jbc.M112.363721