Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1.8 million participants

Y. Lu, K. Hajifathalian, M. Ezzati, M. Woodward, E.B. Rimm, G. Danaei, R. Selmer, B.H. Strand, Z. Fang, D.F. Gu, R. Huxley, Y. Imai, H.C. Kim, T.H. Lam, W.H. Pan, A. Rodgers, I. Suh, H. Ueshima, H. Maegawa, A. OkayamaN. Aoki, M. Nakamura, Z.S. Wu, C.H. Yao, M. Luszcz, T.A. Welborn, Z. Tang, L.S. Liu, J.X. Xie, S. Ameratunga, S. Macmahon, R. Norton, G. Whitlock, Matthew Knuiman, Mark Divitini, H. Christensen, X.G. Wu, X.H. Yu, J. Zhou, A. Tamakoshi, L.Q. Chen, G.L. Shan, Z.L. Wu, P. Sritara, X.F. Duan, R. Jackson, Y.H. Li, C.Q. Jiang, H. Arima, M. Iida, Y. Kiyohara, S.C. Ho, J. Woo, Z. Hong, M.S. Huang, B. Zhou, J.L. Fuh, S.R. Choudhury, Y. Kita, S.H. Jee, I.S. Kim, G.G. Giles, T. Hashimoto, K. Sakata, A. Dobson, T. Ohkubo, A. Hozawa, K. Jamrozik, Michael Hobbs, Robyn Broadhurst, K. Nakachi, X.H. Fang, S.C. Li, Q.D. Yang, Z.M. Chen, H. Tanaka, A. Nozaki, H. Horibe, Y. Matsutani, M. Kagaya, K. Hughes, J. Lee, S.K. Chew, D. Heng, H.Y. Zhang, B.F. Zhou, K. Shimamoto, S. Saitoh, Z.Z. Li, P. Norman, Y. He, S.X. Yao, E.D. Parker, M.A. Pereira, J. Stevens, D.B. Panagiotakos, C. Pitsavos, J.R. Attia, C.A. D'Este, Z. Zhang, E. Clays, D.A.O. De Bacquer, K. Van Herck, M.L. Divitini, M.W. Knuiman, H.I. Morrison, F. Wang, S-Y. Chuang, W-H. Pan, W-T. Yeh, Z. Chen, M.C. Smith, M. Zhou, W. Wang, X-T. Zhang, D. Zhao, S.E. Vollset, S.C. Fuchs, F.D. Fuchs, L.B. Moreira, I.A. Dontas, C.A. Dontas, A.G. Kafatos, J. Moschandreas, M. Lanti, A. Menotti, D. Kromhout, M.K. Jensen, K. Overvad, A. Tjonneland, J. Klotsche, H-U. Wittchen, S. Fischer, M. Hanefeld, U. Schwanebeck, L.A. Simons, J. Simons, R. Bender, S. Matthies, A. Nissinen, H.K. Tolonen, J. Tuomilehto, J.H. Fuller, S.S. Soedamah-Muthu, K. Kotseva, M.L. Bots, K.G.M. Moons, M. Heliovaara, P.B. Knekt, H. Rissanen, J.E. Ferrie, M.J. Shipley, G.D. Smith, S. Johansson, G. Lappas, A. Rosengren, A. Sham, R.H.Y. Yu, J. Hata, T. Ninomiya, S. Hoshide, K. Kario, D. Rastenyte, A. Tamosiunas, G. De Simone, R.B. Devereux, E. Gerdts, D.M. Colquhoun, A.C. Keech, A.C. Kirby, K. Mizuno, H. Nakamura, S. Uchiyama, J.K. Bassett, A.M. Hodge, L. Wilhelmsen, S.S. Dhaliwal, Timothy Welborn, Y. Nakamura, A. Kadota, T. Okamura, M.S. Sandvei, A. Vik, B. Morkedal, P.R. Romundstad, M.S.V. Elkind, H. Gardener, R.L. Sacco, A. Mignano, S. Novo, M. Rizzo, G. Assmann, H. Schulte, L. Lissner, I. Skoog, V. Sundh, A. Marin, M.J. Medrano, A. Hofman, M. Kuningas, B.H. Stricker, Y. Van Der Graaf, F.L.J. Visseren, J.J.M. Lee, W. Bemelmans, L.C.P.G.M. De Groot, E.L. De Hollander, H. Adachi, Y. Hirai, F. Azizi, F. Hadaegh, D. Khalili, E.B. Mathiesen, I. Njolstad, T. Wilsgaard, G. Can, A. Onat, J. Arnlov, J. Sundstrom, H.W. Blackburn, D.R. Jacobs, M.R. Averna, A.B. Cefalu, D. Noto, H. Concin, G. Nagel, H. Ulmer, R.E. Krasnow, G.E. Swan, M. Kivimaki, G.D. Batty, N. Milic, M.C. Ostojic, B. Parapid, J.M. Geleijnse, E. Waterham, E.J. Feskens

Research output: Contribution to journalArticle

489 Citations (Scopus)
Original languageEnglish
Pages (from-to)970-983
JournalThe Lancet
Volume383
DOIs
Publication statusPublished - 2014

Cite this

Lu, Y., Hajifathalian, K., Ezzati, M., Woodward, M., Rimm, E. B., Danaei, G., Selmer, R., Strand, B. H., Fang, Z., Gu, D. F., Huxley, R., Imai, Y., Kim, H. C., Lam, T. H., Pan, W. H., Rodgers, A., Suh, I., Ueshima, H., Maegawa, H., ... Feskens, E. J. (2014). Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1.8 million participants. The Lancet, 383, 970-983. https://doi.org/10.1016/ S0140-6736(13)61836-X