TY - JOUR
T1 - Medicinal cannabis in neurodegenerative disorders
T2 - an open label, dose finding, safety and efficacy study
AU - Panegyres, Peter K.
AU - Lind, Kerry L.
AU - MacFarlane, Cheryl A.
AU - Gurney, Allana L.
PY - 2024
Y1 - 2024
N2 - Aim: Currently, there exist no curative treatments for neurodegenerative disorders. Recently, there has been a resurgence of interest in the use of medicinal cannabis to improve neurological conditions. Methods: A 12-month, open label, dose-finding, safety and efficacy study was conducted including 48 subjects with a variety of neurodegenerative disorders. Results: In our participants, we observed a reduction in pain, improved sleep, enhanced well-being and less agitation. Conclusion: Our findings suggest that medicinal cannabis might be useful in patients with neurodegenerative disorders in controlling pain, enhancing sleep, reducing difficult behaviors, controlling unusual and complex symptoms when other treatments have failed–this offers medicinal cannabis a role in palliation.
AB - Aim: Currently, there exist no curative treatments for neurodegenerative disorders. Recently, there has been a resurgence of interest in the use of medicinal cannabis to improve neurological conditions. Methods: A 12-month, open label, dose-finding, safety and efficacy study was conducted including 48 subjects with a variety of neurodegenerative disorders. Results: In our participants, we observed a reduction in pain, improved sleep, enhanced well-being and less agitation. Conclusion: Our findings suggest that medicinal cannabis might be useful in patients with neurodegenerative disorders in controlling pain, enhancing sleep, reducing difficult behaviors, controlling unusual and complex symptoms when other treatments have failed–this offers medicinal cannabis a role in palliation.
KW - medicinal cannabis
KW - neurodegenerative disorders
KW - open label
KW - pain
KW - sleep
UR - http://www.scopus.com/inward/record.url?scp=85193374873&partnerID=8YFLogxK
U2 - 10.2217/nmt-2023-0011
DO - 10.2217/nmt-2023-0011
M3 - Article
C2 - 38639578
AN - SCOPUS:85193374873
SN - 1758-2024
VL - 14
SP - 35
EP - 46
JO - Neurodegenerative Disease Management
JF - Neurodegenerative Disease Management
IS - 2
ER -